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Low-dose LPS alleviates early brain injury after SAH by modulating microglial M1/M2 polarization via USP19/FOXO1/IL-10/IL-10R1 signaling
BACKGROUND: Low-dose lipopolysaccharide (LPS) protects against early brain injury (EBI) after subarachnoid hemorrhage (SAH). However, the mechanism underlying the neuroprotective roles of low-dose LPS remain largely undefined. METHODS: A SAH mice model was established and the pathological changes of...
Autores principales: | Tao, Weihua, Zhang, Guibo, Liu, Chengyuan, Jin, Lide, Li, Xuehua, Yang, Shuaifeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10494318/ https://www.ncbi.nlm.nih.gov/pubmed/37672892 http://dx.doi.org/10.1016/j.redox.2023.102863 |
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