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Acetylcholinesterase inhibition protects against trastuzumab-induced cardiotoxicity through reducing multiple programmed cell death pathways
BACKGROUND: Trastuzumab (Trz)-induced cardiotoxicity (TIC) is one of the most common adverse effects of targeted anticancer agents. Although oxidative stress, inflammation, mitochondrial dysfunction, apoptosis, and ferroptosis have been identified as potential mechanisms underlying TIC, the roles of...
Autores principales: | Khuanjing, Thawatchai, Maneechote, Chayodom, Ongnok, Benjamin, Prathumsap, Nanthip, Arinno, Apiwan, Chunchai, Titikorn, Arunsak, Busarin, Chattipakorn, Siriporn C., Chattipakorn, Nipon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10494358/ https://www.ncbi.nlm.nih.gov/pubmed/37691124 http://dx.doi.org/10.1186/s10020-023-00686-7 |
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