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Acetylcholinesterase inhibition protects against trastuzumab-induced cardiotoxicity through reducing multiple programmed cell death pathways

BACKGROUND: Trastuzumab (Trz)-induced cardiotoxicity (TIC) is one of the most common adverse effects of targeted anticancer agents. Although oxidative stress, inflammation, mitochondrial dysfunction, apoptosis, and ferroptosis have been identified as potential mechanisms underlying TIC, the roles of...

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Detalles Bibliográficos
Autores principales:	Khuanjing, Thawatchai, Maneechote, Chayodom, Ongnok, Benjamin, Prathumsap, Nanthip, Arinno, Apiwan, Chunchai, Titikorn, Arunsak, Busarin, Chattipakorn, Siriporn C., Chattipakorn, Nipon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10494358/ https://www.ncbi.nlm.nih.gov/pubmed/37691124 http://dx.doi.org/10.1186/s10020-023-00686-7

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