Position dependent dyspnea and hypoxemia

A 63-year-old man was analyzed for platypnea-orthodeoxia syndrome (POS). A complete obstruction due to bronchial carcinoma was found in the left main bronchus with bronchoscopy. After left sided pneumonectomy POS resolved completely. Historical reports suggest increased shunting through the left lun...

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Detalles Bibliográficos
Autores principales: Hoppe, Bart P.C., van Dam, Monica J.M., Dik, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10494457/
https://www.ncbi.nlm.nih.gov/pubmed/37701457
http://dx.doi.org/10.1016/j.rmcr.2023.101912
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author Hoppe, Bart P.C.
van Dam, Monica J.M.
Dik, Hans
author_facet Hoppe, Bart P.C.
van Dam, Monica J.M.
Dik, Hans
author_sort Hoppe, Bart P.C.
collection PubMed
description A 63-year-old man was analyzed for platypnea-orthodeoxia syndrome (POS). A complete obstruction due to bronchial carcinoma was found in the left main bronchus with bronchoscopy. After left sided pneumonectomy POS resolved completely. Historical reports suggest increased shunting through the left lung could occur in the upright position caused by decreased compression of the left pulmonary artery due to the central bronchial carcinoma. Partially absent hypoxic vasoconstriction was confirmed in this case and suggests (without a relevant shunt through a patent foramen ovale) this ‘historical’ hypothesis could explain the POS due to increased shunting in the upright position in this patient.
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spelling pubmed-104944572023-09-12 Position dependent dyspnea and hypoxemia Hoppe, Bart P.C. van Dam, Monica J.M. Dik, Hans Respir Med Case Rep Case Report A 63-year-old man was analyzed for platypnea-orthodeoxia syndrome (POS). A complete obstruction due to bronchial carcinoma was found in the left main bronchus with bronchoscopy. After left sided pneumonectomy POS resolved completely. Historical reports suggest increased shunting through the left lung could occur in the upright position caused by decreased compression of the left pulmonary artery due to the central bronchial carcinoma. Partially absent hypoxic vasoconstriction was confirmed in this case and suggests (without a relevant shunt through a patent foramen ovale) this ‘historical’ hypothesis could explain the POS due to increased shunting in the upright position in this patient. Elsevier 2023-08-23 /pmc/articles/PMC10494457/ /pubmed/37701457 http://dx.doi.org/10.1016/j.rmcr.2023.101912 Text en © 2023 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Hoppe, Bart P.C.
van Dam, Monica J.M.
Dik, Hans
Position dependent dyspnea and hypoxemia
title Position dependent dyspnea and hypoxemia
title_full Position dependent dyspnea and hypoxemia
title_fullStr Position dependent dyspnea and hypoxemia
title_full_unstemmed Position dependent dyspnea and hypoxemia
title_short Position dependent dyspnea and hypoxemia
title_sort position dependent dyspnea and hypoxemia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10494457/
https://www.ncbi.nlm.nih.gov/pubmed/37701457
http://dx.doi.org/10.1016/j.rmcr.2023.101912
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