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Immune regulator IRF1 contributes to ZBP1-, AIM2-, RIPK1-, and NLRP12-PANoptosome activation and inflammatory cell death (PANoptosis)

The innate immune system provides the first line of defense against pathogens and cellular insults and is activated by pattern recognition receptors sensing pathogen- or damage-associated molecular patterns. This activation can result in inflammation via cytokine release as well as the induction of...

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Detalles Bibliográficos
Autores principales:	Sharma, Bhesh Raj, Karki, Rajendra, Rajesh, Yetirajam, Kanneganti, Thirumala-Devi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10494469/ https://www.ncbi.nlm.nih.gov/pubmed/37557956 http://dx.doi.org/10.1016/j.jbc.2023.105141

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