JMJD2D stabilises and cooperates with HBx protein to promote HBV transcription and replication

BACKGROUND & AIMS: HBV infection is a global health burden. Covalently closed circular DNA (cccDNA) transcriptional regulation is a major cause of poor cure rates of chronic hepatitis B (CHB) infection. Herein, we evaluated whether targeting host factors to achieve functional silencing of cccDNA...

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Detalles Bibliográficos
Autores principales: Kong, Xu, Liu, Zuofeng, Zhang, Ruyi, Xie, Fu’an, Liang, Rubing, Zhang, Yong, Yu, Lingling, Yang, Wensheng, Li, Xi, Chen, Qiang, Li, Bei, Hong, Yilin, Li, Ming, Xia, Xiaogang, Gu, Lingwei, Fu, Lijuan, Li, Xiaohua, Shen, Ye, Wu, Ting, Yu, Chundong, Li, Wengang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10494471/
https://www.ncbi.nlm.nih.gov/pubmed/37701334
http://dx.doi.org/10.1016/j.jhepr.2023.100849

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