Targeting KRAS in pancreatic adenocarcinoma: Progress in demystifying the holy grail

Pancreatic cancer (PC) remains one of the most challenging diseases, with a very poor 5-year overall survival of around 11.5%. Kirsten rat sarcoma virus (KRAS) mutation is seen in 90%-95% of PC patients and plays an important role in cancer cell proliferation, differentiation, metabolism, and surviv...

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Detalles Bibliográficos
Autores principales: Elhariri, Ahmed, Alhaj, Ahmed, Ahn, Daniel, Sonbol, Mohamad Bassam, Bekaii-Saab, Tanios, Wu, Christina, Rutenberg, Michael Scott, Stauffer, John, Starr, Jason, Majeed, Umair, Jones, Jeremy, Borad, Mitesh, Babiker, Hani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2023
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10494558/
https://www.ncbi.nlm.nih.gov/pubmed/37700806
http://dx.doi.org/10.5306/wjco.v14.i8.285

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