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Frontal cutaneous and bone sarcoidosis: an example of the contiguous spread of granulomas

Sarcoidosis is a multisystemic granulomatous disease of unknown origin. It has been argued that the skin is one of the entry doors of the possible antigen that causes sarcoidosis and after entering the skin, the causal agent may progress to the underlying bone. We report four cases with development...

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Autores principales: Braga, Sara, Jeny, Florence, Latrasse, Marjorie, Saidenberg Kermanac’h, Nathalie, Tran Ba, Stéphane, Nunes, Hilario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mattioli 1885 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10494748/
https://www.ncbi.nlm.nih.gov/pubmed/37382068
http://dx.doi.org/10.36141/svdld.v40i2.14594
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author Braga, Sara
Jeny, Florence
Latrasse, Marjorie
Saidenberg Kermanac’h, Nathalie
Tran Ba, Stéphane
Nunes, Hilario
author_facet Braga, Sara
Jeny, Florence
Latrasse, Marjorie
Saidenberg Kermanac’h, Nathalie
Tran Ba, Stéphane
Nunes, Hilario
author_sort Braga, Sara
collection PubMed
description Sarcoidosis is a multisystemic granulomatous disease of unknown origin. It has been argued that the skin is one of the entry doors of the possible antigen that causes sarcoidosis and after entering the skin, the causal agent may progress to the underlying bone. We report four cases with development of sarcoidosis in old scars located on the forehead, and contiguous bone involvement of the frontal bone. In most cases scar sarcoidosis was the first manifestation of the disease, and in most cases it was asymptomatic. Two patients never required treatment, and in all cases the frontal problem improved or remained stable spontaneously or under sarcoidosis treatment. Scar sarcoidosis in the frontal area may have contiguous bone damage. This bone involvement does not seem to be associated with neurological extension.
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spelling pubmed-104947482023-09-12 Frontal cutaneous and bone sarcoidosis: an example of the contiguous spread of granulomas Braga, Sara Jeny, Florence Latrasse, Marjorie Saidenberg Kermanac’h, Nathalie Tran Ba, Stéphane Nunes, Hilario Sarcoidosis Vasc Diffuse Lung Dis Case Series Sarcoidosis is a multisystemic granulomatous disease of unknown origin. It has been argued that the skin is one of the entry doors of the possible antigen that causes sarcoidosis and after entering the skin, the causal agent may progress to the underlying bone. We report four cases with development of sarcoidosis in old scars located on the forehead, and contiguous bone involvement of the frontal bone. In most cases scar sarcoidosis was the first manifestation of the disease, and in most cases it was asymptomatic. Two patients never required treatment, and in all cases the frontal problem improved or remained stable spontaneously or under sarcoidosis treatment. Scar sarcoidosis in the frontal area may have contiguous bone damage. This bone involvement does not seem to be associated with neurological extension. Mattioli 1885 2023 2023-06-29 /pmc/articles/PMC10494748/ /pubmed/37382068 http://dx.doi.org/10.36141/svdld.v40i2.14594 Text en Copyright: © 2023 SARCOIDOSIS VASCULITIS AND DIFFUSE LUNG DISEASES https://creativecommons.org/licenses/by-nc-sa/4.0/This work is licensed under a Creative Commons Attribution 4.0 International License
spellingShingle Case Series
Braga, Sara
Jeny, Florence
Latrasse, Marjorie
Saidenberg Kermanac’h, Nathalie
Tran Ba, Stéphane
Nunes, Hilario
Frontal cutaneous and bone sarcoidosis: an example of the contiguous spread of granulomas
title Frontal cutaneous and bone sarcoidosis: an example of the contiguous spread of granulomas
title_full Frontal cutaneous and bone sarcoidosis: an example of the contiguous spread of granulomas
title_fullStr Frontal cutaneous and bone sarcoidosis: an example of the contiguous spread of granulomas
title_full_unstemmed Frontal cutaneous and bone sarcoidosis: an example of the contiguous spread of granulomas
title_short Frontal cutaneous and bone sarcoidosis: an example of the contiguous spread of granulomas
title_sort frontal cutaneous and bone sarcoidosis: an example of the contiguous spread of granulomas
topic Case Series
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10494748/
https://www.ncbi.nlm.nih.gov/pubmed/37382068
http://dx.doi.org/10.36141/svdld.v40i2.14594
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