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Frontal cutaneous and bone sarcoidosis: an example of the contiguous spread of granulomas
Sarcoidosis is a multisystemic granulomatous disease of unknown origin. It has been argued that the skin is one of the entry doors of the possible antigen that causes sarcoidosis and after entering the skin, the causal agent may progress to the underlying bone. We report four cases with development...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mattioli 1885
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10494748/ https://www.ncbi.nlm.nih.gov/pubmed/37382068 http://dx.doi.org/10.36141/svdld.v40i2.14594 |
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author | Braga, Sara Jeny, Florence Latrasse, Marjorie Saidenberg Kermanac’h, Nathalie Tran Ba, Stéphane Nunes, Hilario |
author_facet | Braga, Sara Jeny, Florence Latrasse, Marjorie Saidenberg Kermanac’h, Nathalie Tran Ba, Stéphane Nunes, Hilario |
author_sort | Braga, Sara |
collection | PubMed |
description | Sarcoidosis is a multisystemic granulomatous disease of unknown origin. It has been argued that the skin is one of the entry doors of the possible antigen that causes sarcoidosis and after entering the skin, the causal agent may progress to the underlying bone. We report four cases with development of sarcoidosis in old scars located on the forehead, and contiguous bone involvement of the frontal bone. In most cases scar sarcoidosis was the first manifestation of the disease, and in most cases it was asymptomatic. Two patients never required treatment, and in all cases the frontal problem improved or remained stable spontaneously or under sarcoidosis treatment. Scar sarcoidosis in the frontal area may have contiguous bone damage. This bone involvement does not seem to be associated with neurological extension. |
format | Online Article Text |
id | pubmed-10494748 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Mattioli 1885 |
record_format | MEDLINE/PubMed |
spelling | pubmed-104947482023-09-12 Frontal cutaneous and bone sarcoidosis: an example of the contiguous spread of granulomas Braga, Sara Jeny, Florence Latrasse, Marjorie Saidenberg Kermanac’h, Nathalie Tran Ba, Stéphane Nunes, Hilario Sarcoidosis Vasc Diffuse Lung Dis Case Series Sarcoidosis is a multisystemic granulomatous disease of unknown origin. It has been argued that the skin is one of the entry doors of the possible antigen that causes sarcoidosis and after entering the skin, the causal agent may progress to the underlying bone. We report four cases with development of sarcoidosis in old scars located on the forehead, and contiguous bone involvement of the frontal bone. In most cases scar sarcoidosis was the first manifestation of the disease, and in most cases it was asymptomatic. Two patients never required treatment, and in all cases the frontal problem improved or remained stable spontaneously or under sarcoidosis treatment. Scar sarcoidosis in the frontal area may have contiguous bone damage. This bone involvement does not seem to be associated with neurological extension. Mattioli 1885 2023 2023-06-29 /pmc/articles/PMC10494748/ /pubmed/37382068 http://dx.doi.org/10.36141/svdld.v40i2.14594 Text en Copyright: © 2023 SARCOIDOSIS VASCULITIS AND DIFFUSE LUNG DISEASES https://creativecommons.org/licenses/by-nc-sa/4.0/This work is licensed under a Creative Commons Attribution 4.0 International License |
spellingShingle | Case Series Braga, Sara Jeny, Florence Latrasse, Marjorie Saidenberg Kermanac’h, Nathalie Tran Ba, Stéphane Nunes, Hilario Frontal cutaneous and bone sarcoidosis: an example of the contiguous spread of granulomas |
title | Frontal cutaneous and bone sarcoidosis: an example of the contiguous spread of granulomas |
title_full | Frontal cutaneous and bone sarcoidosis: an example of the contiguous spread of granulomas |
title_fullStr | Frontal cutaneous and bone sarcoidosis: an example of the contiguous spread of granulomas |
title_full_unstemmed | Frontal cutaneous and bone sarcoidosis: an example of the contiguous spread of granulomas |
title_short | Frontal cutaneous and bone sarcoidosis: an example of the contiguous spread of granulomas |
title_sort | frontal cutaneous and bone sarcoidosis: an example of the contiguous spread of granulomas |
topic | Case Series |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10494748/ https://www.ncbi.nlm.nih.gov/pubmed/37382068 http://dx.doi.org/10.36141/svdld.v40i2.14594 |
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