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Predictors of one-year mortality following hip fracture surgery in elderly

BACKGROUND: Understanding mortality risk factors is critical to reducing mortality among elderly hip fracture patients. To investigate the effects of admission and post-operative levels of distribution width of red blood cells (RDW), albumin, and RDW/albumin (RA) ratio on predicting 1-year mortality...

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Autores principales: Özel, Mehmet, Altıntaş, Mustafa, Tatlıparmak, Ali Cankut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10494834/
https://www.ncbi.nlm.nih.gov/pubmed/37701840
http://dx.doi.org/10.7717/peerj.16008
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author Özel, Mehmet
Altıntaş, Mustafa
Tatlıparmak, Ali Cankut
author_facet Özel, Mehmet
Altıntaş, Mustafa
Tatlıparmak, Ali Cankut
author_sort Özel, Mehmet
collection PubMed
description BACKGROUND: Understanding mortality risk factors is critical to reducing mortality among elderly hip fracture patients. To investigate the effects of admission and post-operative levels of distribution width of red blood cells (RDW), albumin, and RDW/albumin (RA) ratio on predicting 1-year mortality following hip fracture surgery. METHODS: A retrospective study was conducted on 275 elderly patients who underwent hip fracture surgery in a tertiary hospital between January 2018 and January 2022. Deaths within one year of hip fracture were defined as the deceased group. The survivors were defined as those who survived for at least one year. The relationship between admission and post-operative levels of RDW, albumin, RA, and mortality within one year after hip surgery was assessed statistically, including binary logistic regression analysis. The study also assessed other factors related to mortality. RESULTS: One-year mortality was 34.7%. There was a 3.03-year (95% CI [1.32–4.75]) difference between the deceased (79.55 ± 8.36 years) and survivors (82.58 ± 7.41 years) (p < 0.001). In the deceased group, the mean hemoglobin (HGB) values at admission (p = 0.022) and post-operative (p = 0.04) were significantly lower. RDW values at admission (p = 0.001) and post-op (p = 0.001) were significantly lower in the survivor group. The mean albumin values at admission (p < 0.001) and post-operative (p < 0.001) in the survivor group were significantly higher than in the deceased group. A significant difference was found between the survivor group and the deceased group in terms of mean RA ratio at admission and post-operative (p < 0.001). Based on binary logistic regression analysis, presence of chronic obstructive pulmonary disease (COPD) (OR 3.73, 95% CI [1.8–7.76]), RDW (OR 1.78, 95% CI [1.48–2.14]), and albumin (OR 0.81, 95% CI [0.75–0.87]), values at admission were found to be independent predictors of 1-year mortality in elderly patients with hip fracture. CONCLUSION: Based on this study, presence of COPD, higher RDW, and lower albumin levels at admission were independent predictors of 1-year mortality following hip fracture surgery in the elderly.
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spelling pubmed-104948342023-09-12 Predictors of one-year mortality following hip fracture surgery in elderly Özel, Mehmet Altıntaş, Mustafa Tatlıparmak, Ali Cankut PeerJ Epidemiology BACKGROUND: Understanding mortality risk factors is critical to reducing mortality among elderly hip fracture patients. To investigate the effects of admission and post-operative levels of distribution width of red blood cells (RDW), albumin, and RDW/albumin (RA) ratio on predicting 1-year mortality following hip fracture surgery. METHODS: A retrospective study was conducted on 275 elderly patients who underwent hip fracture surgery in a tertiary hospital between January 2018 and January 2022. Deaths within one year of hip fracture were defined as the deceased group. The survivors were defined as those who survived for at least one year. The relationship between admission and post-operative levels of RDW, albumin, RA, and mortality within one year after hip surgery was assessed statistically, including binary logistic regression analysis. The study also assessed other factors related to mortality. RESULTS: One-year mortality was 34.7%. There was a 3.03-year (95% CI [1.32–4.75]) difference between the deceased (79.55 ± 8.36 years) and survivors (82.58 ± 7.41 years) (p < 0.001). In the deceased group, the mean hemoglobin (HGB) values at admission (p = 0.022) and post-operative (p = 0.04) were significantly lower. RDW values at admission (p = 0.001) and post-op (p = 0.001) were significantly lower in the survivor group. The mean albumin values at admission (p < 0.001) and post-operative (p < 0.001) in the survivor group were significantly higher than in the deceased group. A significant difference was found between the survivor group and the deceased group in terms of mean RA ratio at admission and post-operative (p < 0.001). Based on binary logistic regression analysis, presence of chronic obstructive pulmonary disease (COPD) (OR 3.73, 95% CI [1.8–7.76]), RDW (OR 1.78, 95% CI [1.48–2.14]), and albumin (OR 0.81, 95% CI [0.75–0.87]), values at admission were found to be independent predictors of 1-year mortality in elderly patients with hip fracture. CONCLUSION: Based on this study, presence of COPD, higher RDW, and lower albumin levels at admission were independent predictors of 1-year mortality following hip fracture surgery in the elderly. PeerJ Inc. 2023-09-08 /pmc/articles/PMC10494834/ /pubmed/37701840 http://dx.doi.org/10.7717/peerj.16008 Text en ©2023 Özel et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited.
spellingShingle Epidemiology
Özel, Mehmet
Altıntaş, Mustafa
Tatlıparmak, Ali Cankut
Predictors of one-year mortality following hip fracture surgery in elderly
title Predictors of one-year mortality following hip fracture surgery in elderly
title_full Predictors of one-year mortality following hip fracture surgery in elderly
title_fullStr Predictors of one-year mortality following hip fracture surgery in elderly
title_full_unstemmed Predictors of one-year mortality following hip fracture surgery in elderly
title_short Predictors of one-year mortality following hip fracture surgery in elderly
title_sort predictors of one-year mortality following hip fracture surgery in elderly
topic Epidemiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10494834/
https://www.ncbi.nlm.nih.gov/pubmed/37701840
http://dx.doi.org/10.7717/peerj.16008
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