Cargando…
Predictors of one-year mortality following hip fracture surgery in elderly
BACKGROUND: Understanding mortality risk factors is critical to reducing mortality among elderly hip fracture patients. To investigate the effects of admission and post-operative levels of distribution width of red blood cells (RDW), albumin, and RDW/albumin (RA) ratio on predicting 1-year mortality...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10494834/ https://www.ncbi.nlm.nih.gov/pubmed/37701840 http://dx.doi.org/10.7717/peerj.16008 |
_version_ | 1785104782399111168 |
---|---|
author | Özel, Mehmet Altıntaş, Mustafa Tatlıparmak, Ali Cankut |
author_facet | Özel, Mehmet Altıntaş, Mustafa Tatlıparmak, Ali Cankut |
author_sort | Özel, Mehmet |
collection | PubMed |
description | BACKGROUND: Understanding mortality risk factors is critical to reducing mortality among elderly hip fracture patients. To investigate the effects of admission and post-operative levels of distribution width of red blood cells (RDW), albumin, and RDW/albumin (RA) ratio on predicting 1-year mortality following hip fracture surgery. METHODS: A retrospective study was conducted on 275 elderly patients who underwent hip fracture surgery in a tertiary hospital between January 2018 and January 2022. Deaths within one year of hip fracture were defined as the deceased group. The survivors were defined as those who survived for at least one year. The relationship between admission and post-operative levels of RDW, albumin, RA, and mortality within one year after hip surgery was assessed statistically, including binary logistic regression analysis. The study also assessed other factors related to mortality. RESULTS: One-year mortality was 34.7%. There was a 3.03-year (95% CI [1.32–4.75]) difference between the deceased (79.55 ± 8.36 years) and survivors (82.58 ± 7.41 years) (p < 0.001). In the deceased group, the mean hemoglobin (HGB) values at admission (p = 0.022) and post-operative (p = 0.04) were significantly lower. RDW values at admission (p = 0.001) and post-op (p = 0.001) were significantly lower in the survivor group. The mean albumin values at admission (p < 0.001) and post-operative (p < 0.001) in the survivor group were significantly higher than in the deceased group. A significant difference was found between the survivor group and the deceased group in terms of mean RA ratio at admission and post-operative (p < 0.001). Based on binary logistic regression analysis, presence of chronic obstructive pulmonary disease (COPD) (OR 3.73, 95% CI [1.8–7.76]), RDW (OR 1.78, 95% CI [1.48–2.14]), and albumin (OR 0.81, 95% CI [0.75–0.87]), values at admission were found to be independent predictors of 1-year mortality in elderly patients with hip fracture. CONCLUSION: Based on this study, presence of COPD, higher RDW, and lower albumin levels at admission were independent predictors of 1-year mortality following hip fracture surgery in the elderly. |
format | Online Article Text |
id | pubmed-10494834 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | PeerJ Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-104948342023-09-12 Predictors of one-year mortality following hip fracture surgery in elderly Özel, Mehmet Altıntaş, Mustafa Tatlıparmak, Ali Cankut PeerJ Epidemiology BACKGROUND: Understanding mortality risk factors is critical to reducing mortality among elderly hip fracture patients. To investigate the effects of admission and post-operative levels of distribution width of red blood cells (RDW), albumin, and RDW/albumin (RA) ratio on predicting 1-year mortality following hip fracture surgery. METHODS: A retrospective study was conducted on 275 elderly patients who underwent hip fracture surgery in a tertiary hospital between January 2018 and January 2022. Deaths within one year of hip fracture were defined as the deceased group. The survivors were defined as those who survived for at least one year. The relationship between admission and post-operative levels of RDW, albumin, RA, and mortality within one year after hip surgery was assessed statistically, including binary logistic regression analysis. The study also assessed other factors related to mortality. RESULTS: One-year mortality was 34.7%. There was a 3.03-year (95% CI [1.32–4.75]) difference between the deceased (79.55 ± 8.36 years) and survivors (82.58 ± 7.41 years) (p < 0.001). In the deceased group, the mean hemoglobin (HGB) values at admission (p = 0.022) and post-operative (p = 0.04) were significantly lower. RDW values at admission (p = 0.001) and post-op (p = 0.001) were significantly lower in the survivor group. The mean albumin values at admission (p < 0.001) and post-operative (p < 0.001) in the survivor group were significantly higher than in the deceased group. A significant difference was found between the survivor group and the deceased group in terms of mean RA ratio at admission and post-operative (p < 0.001). Based on binary logistic regression analysis, presence of chronic obstructive pulmonary disease (COPD) (OR 3.73, 95% CI [1.8–7.76]), RDW (OR 1.78, 95% CI [1.48–2.14]), and albumin (OR 0.81, 95% CI [0.75–0.87]), values at admission were found to be independent predictors of 1-year mortality in elderly patients with hip fracture. CONCLUSION: Based on this study, presence of COPD, higher RDW, and lower albumin levels at admission were independent predictors of 1-year mortality following hip fracture surgery in the elderly. PeerJ Inc. 2023-09-08 /pmc/articles/PMC10494834/ /pubmed/37701840 http://dx.doi.org/10.7717/peerj.16008 Text en ©2023 Özel et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited. |
spellingShingle | Epidemiology Özel, Mehmet Altıntaş, Mustafa Tatlıparmak, Ali Cankut Predictors of one-year mortality following hip fracture surgery in elderly |
title | Predictors of one-year mortality following hip fracture surgery in elderly |
title_full | Predictors of one-year mortality following hip fracture surgery in elderly |
title_fullStr | Predictors of one-year mortality following hip fracture surgery in elderly |
title_full_unstemmed | Predictors of one-year mortality following hip fracture surgery in elderly |
title_short | Predictors of one-year mortality following hip fracture surgery in elderly |
title_sort | predictors of one-year mortality following hip fracture surgery in elderly |
topic | Epidemiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10494834/ https://www.ncbi.nlm.nih.gov/pubmed/37701840 http://dx.doi.org/10.7717/peerj.16008 |
work_keys_str_mv | AT ozelmehmet predictorsofoneyearmortalityfollowinghipfracturesurgeryinelderly AT altıntasmustafa predictorsofoneyearmortalityfollowinghipfracturesurgeryinelderly AT tatlıparmakalicankut predictorsofoneyearmortalityfollowinghipfracturesurgeryinelderly |