Fluorescence microscope light source based on integrated LED

An LED-integrated excitation cube (LEC) was designed to address the limitations of conventional fluorescence lamps. The LEC has a decentralized structure, high optical power density, and efficient illumination. The optical efficiency of LECs is 1–2 orders of magnitude higher than that of mercury lam...

Descripción completa

Detalles Bibliográficos
Autores principales: Zi, Jianchen, Bi, Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
News & Views
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495340/
https://www.ncbi.nlm.nih.gov/pubmed/37696803
http://dx.doi.org/10.1038/s41377-023-01245-9
_version_ 1785104872290385920
author Zi, Jianchen
Bi, Hai
author_facet Zi, Jianchen
Bi, Hai
author_sort Zi, Jianchen
collection PubMed
description An LED-integrated excitation cube (LEC) was designed to address the limitations of conventional fluorescence lamps. The LEC has a decentralized structure, high optical power density, and efficient illumination. The optical efficiency of LECs is 1–2 orders of magnitude higher than that of mercury lamps, enabling high-quality fluorescence imaging with spectral coverage from UV to red. LECs can be easily installed on commercial fluorescence microscopes by replacing conventional fluorescence filter cubes, and a built-in LEC driver can identify the types of LEDs in different spectral bands to adopt optimal operating conditions.
format Online
Article
Text
id pubmed-10495340
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-104953402023-09-13 Fluorescence microscope light source based on integrated LED Zi, Jianchen Bi, Hai Light Sci Appl News & Views An LED-integrated excitation cube (LEC) was designed to address the limitations of conventional fluorescence lamps. The LEC has a decentralized structure, high optical power density, and efficient illumination. The optical efficiency of LECs is 1–2 orders of magnitude higher than that of mercury lamps, enabling high-quality fluorescence imaging with spectral coverage from UV to red. LECs can be easily installed on commercial fluorescence microscopes by replacing conventional fluorescence filter cubes, and a built-in LEC driver can identify the types of LEDs in different spectral bands to adopt optimal operating conditions. Nature Publishing Group UK 2023-09-12 /pmc/articles/PMC10495340/ /pubmed/37696803 http://dx.doi.org/10.1038/s41377-023-01245-9 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle News & Views
Zi, Jianchen
Bi, Hai
Fluorescence microscope light source based on integrated LED
title Fluorescence microscope light source based on integrated LED
title_full Fluorescence microscope light source based on integrated LED
title_fullStr Fluorescence microscope light source based on integrated LED
title_full_unstemmed Fluorescence microscope light source based on integrated LED
title_short Fluorescence microscope light source based on integrated LED
title_sort fluorescence microscope light source based on integrated led
topic News & Views
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495340/
https://www.ncbi.nlm.nih.gov/pubmed/37696803
http://dx.doi.org/10.1038/s41377-023-01245-9
work_keys_str_mv AT zijianchen fluorescencemicroscopelightsourcebasedonintegratedled
AT bihai fluorescencemicroscopelightsourcebasedonintegratedled

Ejemplares similares