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Linkage analysis using whole exome sequencing data implicates SLC17A1, SLC17A3, TATDN2 and TMEM131L in type 1 diabetes in Kuwaiti families

Type 1 diabetes (T1D) is characterized by the progressive destruction of pancreatic β-cells, leading to insulin deficiency and lifelong dependency on exogenous insulin. Higher estimates of heritability rates in monozygotic twins, followed by dizygotic twins and sib-pairs, indicate the role of geneti...

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Detalles Bibliográficos
Autores principales:	Hebbar, Prashantha, Nizam, Rasheeba, John, Sumi Elsa, Antony, Dinu, Dashti, Mohammad, Channanath, Arshad, Shaltout, Azza, Al-Khandari, Hessa, Koistinen, Heikki A., Tuomilehto, Jaakko, Alsmadi, Osama, Thanaraj, Thangavel Alphonse, Al-Mulla, Fahd
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495342/ https://www.ncbi.nlm.nih.gov/pubmed/37696853 http://dx.doi.org/10.1038/s41598-023-42255-2

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