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High risk clear cell renal cell carcinoma microenvironments contain protumour immunophenotypes lacking specific immune checkpoints
Perioperative immune checkpoint inhibitor (ICI) trials for intermediate high-risk clear cell renal cell carcinoma (ccRCC) have failed to consistently demonstrate improved patient outcomes. These unsuccessful ICI trials suggest that the tumour infiltrating immunophenotypes, termed here as the immune...
Autores principales: | Raghubar, Arti M., Matigian, Nicholas A., Crawford, Joanna, Francis, Leo, Ellis, Robert, Healy, Helen G., Kassianos, Andrew J., Ng, Monica S. Y., Roberts, Matthew J., Wood, Simon, Mallett, Andrew J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495390/ https://www.ncbi.nlm.nih.gov/pubmed/37696903 http://dx.doi.org/10.1038/s41698-023-00441-5 |
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