Let-7 enhances murine anti-tumor CD8 T cell responses by promoting memory and antagonizing terminal differentiation

The success of the CD8 T cell-mediated immune response against infections and tumors depends on the formation of a long-lived memory pool, and the protection of effector cells from exhaustion. The advent of checkpoint blockade therapy has significantly improved anti-tumor therapeutic outcomes by rev...

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Detalles Bibliográficos
Autores principales: Wells, Alexandria C., Hioki, Kaito A., Angelou, Constance C., Lynch, Adam C., Liang, Xueting, Ryan, Daniel J., Thesmar, Iris, Zhanybekova, Saule, Zuklys, Saulius, Ullom, Jacob, Cheong, Agnes, Mager, Jesse, Hollander, Georg A., Pobezinskaya, Elena L., Pobezinsky, Leonid A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495470/
https://www.ncbi.nlm.nih.gov/pubmed/37696797
http://dx.doi.org/10.1038/s41467-023-40959-7

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