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Functional knockout of long non-coding RNAs with genome editing

An effective loss-of-function study is necessary to investigate the biological function of long non-coding RNA (lncRNA). Various approaches are available, including RNA silencing, antisense oligos, and CRISPR-based genome editing. CRISPR-based genome editing is the most widely used for inactivating...

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Detalles Bibliográficos
Autores principales:	Lyu, Qing Rex, Zhang, Shikuan, Zhang, Zhe, Tang, Zhiyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495571/ https://www.ncbi.nlm.nih.gov/pubmed/37705609 http://dx.doi.org/10.3389/fgene.2023.1242129

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