Peripheral blood CD3+HLADR+ cells and associated gut microbiome species predict response and overall survival to immune checkpoint blockade

BACKGROUND: The search for biomarkers to identify ideal candidates for immune checkpoint inhibitor (ICI) therapy is fundamental. In this study, we analyze peripheral blood CD3+HLADR+ cells (activated T-cells) as a novel biomarker for ICI therapy and how its association to certain gut microbiome spec...

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Detalles Bibliográficos
Autores principales: Gorgulho, Joao, Roderburg, Christoph, Beier, Fabian, Bokemeyer, Carsten, Brümmendorf, Tim H., Luedde, Tom, Loosen, Sven H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495594/
https://www.ncbi.nlm.nih.gov/pubmed/37705980
http://dx.doi.org/10.3389/fimmu.2023.1206953

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495594/
https://www.ncbi.nlm.nih.gov/pubmed/37705980
http://dx.doi.org/10.3389/fimmu.2023.1206953

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