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Peripheral blood CD3+HLADR+ cells and associated gut microbiome species predict response and overall survival to immune checkpoint blockade
BACKGROUND: The search for biomarkers to identify ideal candidates for immune checkpoint inhibitor (ICI) therapy is fundamental. In this study, we analyze peripheral blood CD3+HLADR+ cells (activated T-cells) as a novel biomarker for ICI therapy and how its association to certain gut microbiome spec...
Autores principales: | Gorgulho, Joao, Roderburg, Christoph, Beier, Fabian, Bokemeyer, Carsten, Brümmendorf, Tim H., Luedde, Tom, Loosen, Sven H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495594/ https://www.ncbi.nlm.nih.gov/pubmed/37705980 http://dx.doi.org/10.3389/fimmu.2023.1206953 |
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