Human adipose ECM alleviates radiation-induced skin fibrosis via endothelial cell-mediated M2 macrophage polarization

Radiation therapy can lead to late radiation-induced skin fibrosis (RISF), causing movement restriction, pain, and organ dysfunction. This study evaluated adipose-derived extracellular matrix (Ad-ECM) as a mitigator of RISF. Female C57BL/6J mice that were irradiated developed fibrosis, which was mit...

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Detalles Bibliográficos
Autores principales: Chinnapaka, Somaiah, Yang, Katherine S., Surucu, Yusuf, Bengur, Fuat B., Arellano, José A., Tirmizi, Zayaan, Malekzadeh, Hamid, Epperly, Michael W., Hou, Wen, Greenberger, Joel S., Rubin, J. Peter, Ejaz, Asim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495661/
https://www.ncbi.nlm.nih.gov/pubmed/37705953
http://dx.doi.org/10.1016/j.isci.2023.107660

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