Cardinality optimization in constraint-based modelling: application to human metabolism

MOTIVATION: Several applications in constraint-based modelling can be mathematically formulated as cardinality optimization problems involving the minimization or maximization of the number of nonzeros in a vector. These problems include testing for stoichiometric consistency, testing for flux consi...

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Detalles Bibliográficos
Autores principales: Fleming, Ronan M T, Haraldsdottir, Hulda S, Minh, Le Hoai, Vuong, Phan Tu, Hankemeier, Thomas, Thiele, Ines
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495685/
https://www.ncbi.nlm.nih.gov/pubmed/37697651
http://dx.doi.org/10.1093/bioinformatics/btad450

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