Robust dimethyl‐based multiplex‐DIA doubles single‐cell proteome depth via a reference channel

Single‐cell proteomics aims to characterize biological function and heterogeneity at the level of proteins in an unbiased manner. It is currently limited in proteomic depth, throughput, and robustness, which we address here by a streamlined multiplexed workflow using data‐independent acquisition (mD...

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Detalles Bibliográficos
Autores principales: Thielert, Marvin, Itang, Ericka CM, Ammar, Constantin, Rosenberger, Florian A, Bludau, Isabell, Schweizer, Lisa, Nordmann, Thierry M, Skowronek, Patricia, Wahle, Maria, Zeng, Wen‐Feng, Zhou, Xie‐Xuan, Brunner, Andreas‐David, Richter, Sabrina, Levesque, Mitchell P, Theis, Fabian J, Steger, Martin, Mann, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495816/
https://www.ncbi.nlm.nih.gov/pubmed/37602975
http://dx.doi.org/10.15252/msb.202211503

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