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Structural basis of IRGB10 oligomerization by GTP hydrolysis
Immunity-related GTPase B10 (IRGB10) is a crucial member of the interferon (IFN)-inducible GTPases and plays a vital role in host defense mechanisms. Following infection, IRGB10 is induced by IFNs and functions by liberating pathogenic ligands to activate the inflammasome through direct disruption o...
Autores principales: | Ha, Hyun Ji, Kim, Ju Hyeong, Lee, Gwan Hee, Kim, Subin, Park, Hyun Ho |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495984/ https://www.ncbi.nlm.nih.gov/pubmed/37705969 http://dx.doi.org/10.3389/fimmu.2023.1254415 |
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