COL4A3 Mutation Induced Podocyte Apoptosis by Dysregulation of NADPH Oxidase 4 and MMP-2

INTRODUCTION: Podocyte apoptosis is a common mechanism driving progression in Alport syndrome (AS). This study aimed to investigate the mechanism of podocyte apoptosis caused by COL4A3 mutations. METHODS: We recruited patients with autosomal dominant AS (ADAS). Patients with minimal change disease (...

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Detalles Bibliográficos
Autores principales: Tong, Jun, Zheng, Qimin, Gu, Xiangchen, Weng, Qinjie, Yu, Shuwen, Fang, Zhengying, Jafar Hussain, Hafiz Muhammad, Xu, Jing, Ren, Hong, Chen, Nan, Xie, Jingyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Translational Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10496016/
https://www.ncbi.nlm.nih.gov/pubmed/37705901
http://dx.doi.org/10.1016/j.ekir.2023.06.007

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