Arsenic trioxide demonstrates efficacy in a mouse model of preclinical systemic sclerosis

BACKGROUND: Uncontrolled T-cell activation plays a key role in systemic sclerosis (SSc). Arsenic trioxide (ATO) has immunological effects and has demonstrated potential in preclinical SSc models. In this study, we assessed the efficacy of ATO in Fra2 transgenic (Fra2(TG)) mice, which develop severe...

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Detalles Bibliográficos
Autores principales: Cauvet, Anne, Decellas, Arthur, Guignabert, Christophe, Rongvaux-Gaïda, Dominique, Thuillet, Raphaël, Ottaviani, Mina, Tu, Ly, Rieger, François, Avouac, Jérôme, Allanore, Yannick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10496169/
https://www.ncbi.nlm.nih.gov/pubmed/37700377
http://dx.doi.org/10.1186/s13075-023-03143-2

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