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The relationship between regulatory changes in cis and trans and the evolution of gene expression in humans and chimpanzees

BACKGROUND: Comparative gene expression studies in apes are fundamentally limited by the challenges associated with sampling across different tissues. Here, we used single-cell RNA sequencing of embryoid bodies to collect transcriptomic data from over 70 cell types in three humans and three chimpanz...

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Detalles Bibliográficos
Autores principales:	Barr, Kenneth A., Rhodes, Katherine L., Gilad, Yoav
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10496171/ https://www.ncbi.nlm.nih.gov/pubmed/37697401 http://dx.doi.org/10.1186/s13059-023-03019-3

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