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APOE-ε4 and BIN1 increase risk of Alzheimer’s disease pathology but not specifically of Lewy body pathology

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Lewy body (LB) pathology commonly occurs in individuals with Alzheimer’s disease (AD) pathology. However, it remains unclear which genetic risk factors underlie AD pathology, LB pathology, or AD-LB co-pathology. Notably, whether APOE-ε4 affects risk of LB pathology independently from AD pathology is...

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Detalles Bibliográficos
Autores principales:	Talyansky, Seth, Le Guen, Yann, Kasireddy, Nandita, Belloy, Michael E., Greicius, Michael D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10496176/ https://www.ncbi.nlm.nih.gov/pubmed/37700353 http://dx.doi.org/10.1186/s40478-023-01626-6

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