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Degradation of methylation signals in cryopreserved DNA

BACKGROUND: Blood-based DNA methylation has shown great promise as a biomarker in a wide variety of diseases. Studies of DNA methylation in blood often utilize samples which have been cryopreserved for years or even decades. Therefore, changes in DNA methylation associated with long-term cryopreserv...

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Detalles Bibliográficos
Autores principales:	Lee, Ning Yuan, Hum, Melissa, Tan, Guek Peng, Seah, Ai Choo, Kin, Patricia T., Tan, Ngiap Chuan, Law, Hai-Yang, Lee, Ann S. G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10496221/ https://www.ncbi.nlm.nih.gov/pubmed/37697422 http://dx.doi.org/10.1186/s13148-023-01565-y

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