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Obesity is associated with quality of sperm parameters in men with infertility: a cross-sectional study
BACKGROUND: Previous studies examined the effects of obesity on sperm parameters and reported inconsistent results. Thus, the present study aimed to evaluate the association between obesity and the quality of sperm parameters in infertile men. MATERIAL AND METHODS: The present cross-sectional study...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10496307/ https://www.ncbi.nlm.nih.gov/pubmed/37700299 http://dx.doi.org/10.1186/s12978-023-01664-2 |
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author | Darand, Mina Salimi, Zahra Ghorbani, Moloud Sadeghi, Narges Babaie, Syavash Hosseinzadeh, Mahdieh |
author_facet | Darand, Mina Salimi, Zahra Ghorbani, Moloud Sadeghi, Narges Babaie, Syavash Hosseinzadeh, Mahdieh |
author_sort | Darand, Mina |
collection | PubMed |
description | BACKGROUND: Previous studies examined the effects of obesity on sperm parameters and reported inconsistent results. Thus, the present study aimed to evaluate the association between obesity and the quality of sperm parameters in infertile men. MATERIAL AND METHODS: The present cross-sectional study evaluated 218 infertile men aged 20–50. To this end, the 168-item food frequency questionnaire (FFQ) was utilized to evaluate dietary intake. The anthropometric and biochemical variables were examined using standard methods. Further, the association between obesity and the quality of sperm parameters was evaluated using the controlled linear regression for potential confounders. RESULTS: The normal sperm morphology had a significant inverse association with BMI [adjusted β − 0.074, CI (− 0.141 to − 0.008), P = 0.029] and WC [adjusted β − 0.026, CI (− 0.051 to − 0.001), P = 0.038]. Additionally, visceral fat had a marginal inverse association with normal sperm morphology [adjusted β − 0.065, CI (− 0.138 to 0.008), P = 0.079] and non-progressive sperm motility [adjusted β − 0.241, CI (− 0.495 to 0.014), P = 0.063]. CONCLUSION: Even though the present results indicated that obesity, abdominal obesity, and visceral fat had inverse associations with normal sperm morphology, more mechanism-based studies should be conducted to confirm these findings. |
format | Online Article Text |
id | pubmed-10496307 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-104963072023-09-13 Obesity is associated with quality of sperm parameters in men with infertility: a cross-sectional study Darand, Mina Salimi, Zahra Ghorbani, Moloud Sadeghi, Narges Babaie, Syavash Hosseinzadeh, Mahdieh Reprod Health Research BACKGROUND: Previous studies examined the effects of obesity on sperm parameters and reported inconsistent results. Thus, the present study aimed to evaluate the association between obesity and the quality of sperm parameters in infertile men. MATERIAL AND METHODS: The present cross-sectional study evaluated 218 infertile men aged 20–50. To this end, the 168-item food frequency questionnaire (FFQ) was utilized to evaluate dietary intake. The anthropometric and biochemical variables were examined using standard methods. Further, the association between obesity and the quality of sperm parameters was evaluated using the controlled linear regression for potential confounders. RESULTS: The normal sperm morphology had a significant inverse association with BMI [adjusted β − 0.074, CI (− 0.141 to − 0.008), P = 0.029] and WC [adjusted β − 0.026, CI (− 0.051 to − 0.001), P = 0.038]. Additionally, visceral fat had a marginal inverse association with normal sperm morphology [adjusted β − 0.065, CI (− 0.138 to 0.008), P = 0.079] and non-progressive sperm motility [adjusted β − 0.241, CI (− 0.495 to 0.014), P = 0.063]. CONCLUSION: Even though the present results indicated that obesity, abdominal obesity, and visceral fat had inverse associations with normal sperm morphology, more mechanism-based studies should be conducted to confirm these findings. BioMed Central 2023-09-12 /pmc/articles/PMC10496307/ /pubmed/37700299 http://dx.doi.org/10.1186/s12978-023-01664-2 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Darand, Mina Salimi, Zahra Ghorbani, Moloud Sadeghi, Narges Babaie, Syavash Hosseinzadeh, Mahdieh Obesity is associated with quality of sperm parameters in men with infertility: a cross-sectional study |
title | Obesity is associated with quality of sperm parameters in men with infertility: a cross-sectional study |
title_full | Obesity is associated with quality of sperm parameters in men with infertility: a cross-sectional study |
title_fullStr | Obesity is associated with quality of sperm parameters in men with infertility: a cross-sectional study |
title_full_unstemmed | Obesity is associated with quality of sperm parameters in men with infertility: a cross-sectional study |
title_short | Obesity is associated with quality of sperm parameters in men with infertility: a cross-sectional study |
title_sort | obesity is associated with quality of sperm parameters in men with infertility: a cross-sectional study |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10496307/ https://www.ncbi.nlm.nih.gov/pubmed/37700299 http://dx.doi.org/10.1186/s12978-023-01664-2 |
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