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Obesity is associated with quality of sperm parameters in men with infertility: a cross-sectional study

BACKGROUND: Previous studies examined the effects of obesity on sperm parameters and reported inconsistent results. Thus, the present study aimed to evaluate the association between obesity and the quality of sperm parameters in infertile men. MATERIAL AND METHODS: The present cross-sectional study...

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Autores principales: Darand, Mina, Salimi, Zahra, Ghorbani, Moloud, Sadeghi, Narges, Babaie, Syavash, Hosseinzadeh, Mahdieh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10496307/
https://www.ncbi.nlm.nih.gov/pubmed/37700299
http://dx.doi.org/10.1186/s12978-023-01664-2
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author Darand, Mina
Salimi, Zahra
Ghorbani, Moloud
Sadeghi, Narges
Babaie, Syavash
Hosseinzadeh, Mahdieh
author_facet Darand, Mina
Salimi, Zahra
Ghorbani, Moloud
Sadeghi, Narges
Babaie, Syavash
Hosseinzadeh, Mahdieh
author_sort Darand, Mina
collection PubMed
description BACKGROUND: Previous studies examined the effects of obesity on sperm parameters and reported inconsistent results. Thus, the present study aimed to evaluate the association between obesity and the quality of sperm parameters in infertile men. MATERIAL AND METHODS: The present cross-sectional study evaluated 218 infertile men aged 20–50. To this end, the 168-item food frequency questionnaire (FFQ) was utilized to evaluate dietary intake. The anthropometric and biochemical variables were examined using standard methods. Further, the association between obesity and the quality of sperm parameters was evaluated using the controlled linear regression for potential confounders. RESULTS: The normal sperm morphology had a significant inverse association with BMI [adjusted β − 0.074, CI (− 0.141 to − 0.008), P = 0.029] and WC [adjusted β − 0.026, CI (− 0.051 to − 0.001), P = 0.038]. Additionally, visceral fat had a marginal inverse association with normal sperm morphology [adjusted β − 0.065, CI (− 0.138 to 0.008), P = 0.079] and non-progressive sperm motility [adjusted β − 0.241, CI (− 0.495 to 0.014), P = 0.063]. CONCLUSION: Even though the present results indicated that obesity, abdominal obesity, and visceral fat had inverse associations with normal sperm morphology, more mechanism-based studies should be conducted to confirm these findings.
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spelling pubmed-104963072023-09-13 Obesity is associated with quality of sperm parameters in men with infertility: a cross-sectional study Darand, Mina Salimi, Zahra Ghorbani, Moloud Sadeghi, Narges Babaie, Syavash Hosseinzadeh, Mahdieh Reprod Health Research BACKGROUND: Previous studies examined the effects of obesity on sperm parameters and reported inconsistent results. Thus, the present study aimed to evaluate the association between obesity and the quality of sperm parameters in infertile men. MATERIAL AND METHODS: The present cross-sectional study evaluated 218 infertile men aged 20–50. To this end, the 168-item food frequency questionnaire (FFQ) was utilized to evaluate dietary intake. The anthropometric and biochemical variables were examined using standard methods. Further, the association between obesity and the quality of sperm parameters was evaluated using the controlled linear regression for potential confounders. RESULTS: The normal sperm morphology had a significant inverse association with BMI [adjusted β − 0.074, CI (− 0.141 to − 0.008), P = 0.029] and WC [adjusted β − 0.026, CI (− 0.051 to − 0.001), P = 0.038]. Additionally, visceral fat had a marginal inverse association with normal sperm morphology [adjusted β − 0.065, CI (− 0.138 to 0.008), P = 0.079] and non-progressive sperm motility [adjusted β − 0.241, CI (− 0.495 to 0.014), P = 0.063]. CONCLUSION: Even though the present results indicated that obesity, abdominal obesity, and visceral fat had inverse associations with normal sperm morphology, more mechanism-based studies should be conducted to confirm these findings. BioMed Central 2023-09-12 /pmc/articles/PMC10496307/ /pubmed/37700299 http://dx.doi.org/10.1186/s12978-023-01664-2 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Darand, Mina
Salimi, Zahra
Ghorbani, Moloud
Sadeghi, Narges
Babaie, Syavash
Hosseinzadeh, Mahdieh
Obesity is associated with quality of sperm parameters in men with infertility: a cross-sectional study
title Obesity is associated with quality of sperm parameters in men with infertility: a cross-sectional study
title_full Obesity is associated with quality of sperm parameters in men with infertility: a cross-sectional study
title_fullStr Obesity is associated with quality of sperm parameters in men with infertility: a cross-sectional study
title_full_unstemmed Obesity is associated with quality of sperm parameters in men with infertility: a cross-sectional study
title_short Obesity is associated with quality of sperm parameters in men with infertility: a cross-sectional study
title_sort obesity is associated with quality of sperm parameters in men with infertility: a cross-sectional study
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10496307/
https://www.ncbi.nlm.nih.gov/pubmed/37700299
http://dx.doi.org/10.1186/s12978-023-01664-2
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