Celastrol attenuates streptozotocin-induced diabetic cardiomyopathy in mice by inhibiting the ACE / Ang II / AGTR1 signaling pathway

BACKGROUND: Heart failure is closely correlated with diabetic cardiomyopathy (DCM) and can lead to mortality. Celastrol has long been utilized for the treatment of immune and inflammatory disorders. However, whether celastrol would exert protective effects on DCM has not been determined. This work a...

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Detalles Bibliográficos
Autores principales: Zhao, Xuyong, Huang, Bingwu, Zhang, Jianhua, Xiang, Wenjun, Zhu, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10496318/
https://www.ncbi.nlm.nih.gov/pubmed/37700366
http://dx.doi.org/10.1186/s13098-023-01159-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10496318/
https://www.ncbi.nlm.nih.gov/pubmed/37700366
http://dx.doi.org/10.1186/s13098-023-01159-x

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