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Association between helicobacter pylori infection and primary open-angle glaucoma: a systematic review and meta-analysis
PURPOSE: This systematic review and meta-analysis summarize the evidence for the association between Helicobacter pylori infection and Primary Open-Angle Glaucoma. METHODS: Eligible studies reporting an association between H. pylori infection and Glaucoma were identified through an extensive search...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10496366/ https://www.ncbi.nlm.nih.gov/pubmed/37697285 http://dx.doi.org/10.1186/s12886-023-03111-z |
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author | Ezzati Amini, Elnaz Moradi, Yousef |
author_facet | Ezzati Amini, Elnaz Moradi, Yousef |
author_sort | Ezzati Amini, Elnaz |
collection | PubMed |
description | PURPOSE: This systematic review and meta-analysis summarize the evidence for the association between Helicobacter pylori infection and Primary Open-Angle Glaucoma. METHODS: Eligible studies reporting an association between H. pylori infection and Glaucoma were identified through an extensive search of the Excerpta Medica (EMBASE), Web of Science, Scopus, and PubMed databases and an assessment of the reference list of the top articles until October 2022. Analysis was performed with random effects model using Stata 16. RESULT: Twenty-four studies were included in the systematic review. This study involved 1602 glaucoma patients and 2800 control individuals. The combined RRs of cohort studies and overall combined ORs of case-control studies showed a significant correlation between H. pylori infection and Glaucoma. Subgroup analysis showed that glaucoma patients had a higher risk of having H. pylori infection if they were residents of Europe countries (Cohort: RR: 1.69; 95% CI: 1.3–2.19) and (Case-Control: RR: 3.71; 95% CI: 2.07–6.64), if they had POAG type (Cohort: RR: 1.76; 95% CI: 1.37–2.27) and (Case-Control: RR: 3.71; 95% CI: 2.934.70), if their diagnostic method of HP was histology (Cohort: RR: 1.95; 95% CI: 1.26–3.01) and (Case-Control: RR: 4.06; 95% CI: 2.28–7.22), and if they were over 60 years old (Cohort: RR: 1.63; 95% CI: 1.33-2.00) and (Case-Control: RR: 2.95; 95% CI: 2.27–3.83). DISCUSSION: The results of this meta-analysis suggest a statistically significant association between Helicobacter pylori infection and Primary Open-Angle Glaucoma. |
format | Online Article Text |
id | pubmed-10496366 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-104963662023-09-13 Association between helicobacter pylori infection and primary open-angle glaucoma: a systematic review and meta-analysis Ezzati Amini, Elnaz Moradi, Yousef BMC Ophthalmol Research PURPOSE: This systematic review and meta-analysis summarize the evidence for the association between Helicobacter pylori infection and Primary Open-Angle Glaucoma. METHODS: Eligible studies reporting an association between H. pylori infection and Glaucoma were identified through an extensive search of the Excerpta Medica (EMBASE), Web of Science, Scopus, and PubMed databases and an assessment of the reference list of the top articles until October 2022. Analysis was performed with random effects model using Stata 16. RESULT: Twenty-four studies were included in the systematic review. This study involved 1602 glaucoma patients and 2800 control individuals. The combined RRs of cohort studies and overall combined ORs of case-control studies showed a significant correlation between H. pylori infection and Glaucoma. Subgroup analysis showed that glaucoma patients had a higher risk of having H. pylori infection if they were residents of Europe countries (Cohort: RR: 1.69; 95% CI: 1.3–2.19) and (Case-Control: RR: 3.71; 95% CI: 2.07–6.64), if they had POAG type (Cohort: RR: 1.76; 95% CI: 1.37–2.27) and (Case-Control: RR: 3.71; 95% CI: 2.934.70), if their diagnostic method of HP was histology (Cohort: RR: 1.95; 95% CI: 1.26–3.01) and (Case-Control: RR: 4.06; 95% CI: 2.28–7.22), and if they were over 60 years old (Cohort: RR: 1.63; 95% CI: 1.33-2.00) and (Case-Control: RR: 2.95; 95% CI: 2.27–3.83). DISCUSSION: The results of this meta-analysis suggest a statistically significant association between Helicobacter pylori infection and Primary Open-Angle Glaucoma. BioMed Central 2023-09-11 /pmc/articles/PMC10496366/ /pubmed/37697285 http://dx.doi.org/10.1186/s12886-023-03111-z Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Ezzati Amini, Elnaz Moradi, Yousef Association between helicobacter pylori infection and primary open-angle glaucoma: a systematic review and meta-analysis |
title | Association between helicobacter pylori infection and primary open-angle glaucoma: a systematic review and meta-analysis |
title_full | Association between helicobacter pylori infection and primary open-angle glaucoma: a systematic review and meta-analysis |
title_fullStr | Association between helicobacter pylori infection and primary open-angle glaucoma: a systematic review and meta-analysis |
title_full_unstemmed | Association between helicobacter pylori infection and primary open-angle glaucoma: a systematic review and meta-analysis |
title_short | Association between helicobacter pylori infection and primary open-angle glaucoma: a systematic review and meta-analysis |
title_sort | association between helicobacter pylori infection and primary open-angle glaucoma: a systematic review and meta-analysis |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10496366/ https://www.ncbi.nlm.nih.gov/pubmed/37697285 http://dx.doi.org/10.1186/s12886-023-03111-z |
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