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Combination of bioaffinity ultrafiltration-UFLC-ESI-Q/TOF-MS/MS, in silico docking and multiple complex networks to explore antitumor mechanism of topoisomerase I inhibitors from Artemisiae Scopariae Herba

BACKGROUND: Artemisiae Scopariae Herba (ASH) has been widely used as plant medicine in East Asia with remarkable antitumor activity. However, the underlying mechanisms have not been fully elucidated. METHODS: This study aimed to construct a multi-disciplinary approach to screen topoisomerase I (topo...

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Detalles Bibliográficos
Autores principales:	Chen, Tong, Hu, Jingbo, Wang, Huan, Tan, Nana, Qi, Jianzhao, Wang, Xiaoling, Wang, Le
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10496380/ https://www.ncbi.nlm.nih.gov/pubmed/37700261 http://dx.doi.org/10.1186/s12906-023-04146-x

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