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Prediction of the effects of small molecules on the gut microbiome using machine learning method integrating with optimal molecular features
BACKGROUND: The human gut microbiome (HGM), consisting of trillions of microorganisms, is crucial to human health. Adverse drug use is one of the most important causes of HGM disorder. Thus, it is necessary to identify drugs or compounds with anti-commensal effects on HGM in the early drug discovery...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10496404/ https://www.ncbi.nlm.nih.gov/pubmed/37697256 http://dx.doi.org/10.1186/s12859-023-05455-1 |