A Pyridyl-Furan Series Developed from the Open Global Health Library Block Red Blood Cell Invasion and Protein Trafficking in Plasmodium falciparum through Potential Inhibition of the Parasite’s PI4KIIIB Enzyme

[Image: see text] With the resistance increasing to current antimalarial medicines, there is an urgent need to discover new drug targets and to develop new medicines against these targets. We therefore screened the Open Global Health Library of Merck KGaA, Darmstadt, Germany, of 250 compounds agains...

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Detalles Bibliográficos
Autores principales: Ling, Dawson B., Nguyen, William, Looker, Oliver, Razook, Zahra, McCann, Kirsty, Barry, Alyssa E., Scheurer, Christian, Wittlin, Sergio, Famodimu, Mufuliat Toyin, Delves, Michael J, Bullen, Hayley E., Crabb, Brendan S., Sleebs, Brad E., Gilson, Paul R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10496428/
https://www.ncbi.nlm.nih.gov/pubmed/37639221
http://dx.doi.org/10.1021/acsinfecdis.3c00138

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