ER translocon inhibitor ipomoeassin F inhibits triple-negative breast cancer growth via blocking ER molecular chaperones

Triple-negative breast cancer (TNBC) is an aggressive type of breast cancer where no effective therapy has been developed. Here, we report that the natural product ER translocon inhibitor ipomoeassin F is a selective inhibitor of TNBC cell growth. A proteomic analysis of TNBC cells revealed that ipo...

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Detalles Bibliográficos
Autores principales: Tao, Shishi, Yang, Eun Ju, Zong, Guanghui, Mou, Pui Kei, Ren, Guowen, Pu, Yue, Chen, Liang, Kwon, Ho Jeong, Zhou, Jianhong, Hu, Zhijian, Khosravi, Arman, Zhang, Qingyang, Du, Yuchun, Shi, Wei Q., Shim, Joong Sup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10496495/
https://www.ncbi.nlm.nih.gov/pubmed/37705743
http://dx.doi.org/10.7150/ijbs.82012

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