Apelin Prevents and Alleviates Crystalline Silica-induced Pulmonary Fibrosis via Inhibiting Transforming Growth Factor Beta 1-triggered Fibroblast Activation

Silicosis is a common and ultimately fatal occupational disease, yet the limited therapeutic option remains the major clinical challenge. Apelin, an endogenous ligand of the G-protein-coupled receptor (APJ), is abundantly expressed in diverse organs. The apelin-APJ axis helps to control pathological...

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Detalles Bibliográficos
Autores principales: Shen, Jianling, Feng, Jiayin, Wu, Zhijia, Ou, Yushi, Zhang, Qing, Nong, Qiying, Wu, Qifeng, Li, Cong, Tan, Xiaohui, Ye, Meng, Gao, Zhongxiang, Zhang, Ying, Liang, Weihui, Xia, Lihua, Qin, Yiru, Huang, Yongshun, Zhao, Na, Hu, Shijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10496498/
https://www.ncbi.nlm.nih.gov/pubmed/37705751
http://dx.doi.org/10.7150/ijbs.81436

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