FOXC2-AS1/FOXC2 axis mediates matrix stiffness-induced trans-differentiation of hepatic stellate cells into fibrosis-promoting myofibroblasts

Matrix stiffness is a central modulator of hepatic stellate cells (HSCs) activation and hepatic fibrogenesis. However, the long non-coding RNAs (lncRNAs)-regulated transcriptional factors linking matrix stiffness to alterations in HSCs phenotype are not completely understood. In this study, we inves...

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Detalles Bibliográficos
Autores principales: Sun, Liankang, Li, Yue, Wang, Hao, Xiao, Xuelian, Luo, Xuenan, Yang, Ruida, Li, Jinyan, Ma, Yifei, Liu, Qingguang, Tu, Kangsheng, Shi, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10496501/
https://www.ncbi.nlm.nih.gov/pubmed/37705741
http://dx.doi.org/10.7150/ijbs.81581

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