Radioimmunotherapy Targeting B7-H3 in situ glioma models enhanced antitumor efficacy by Reconstructing the tumor microenvironment

Radionuclide drug conjugates (RDCs) with antibodies serve as a novel approach for the treatment of malignant tumors including glioblastoma. However, RDCs require optimal antibodies to work efficiently. Hu4G4, a novel B7-H3-targeting humanized monoclonal IgG1 antibody, is highly specific for the huma...

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Detalles Bibliográficos
Autores principales: Zheng, Meng, Wang, Yan, Fu, Fengqing, Zhang, Kaijie, Wang, Yanan, Zhao, Shandong, Liu, Qingfeng, Mu, Huiwen, Zhang, Xueguang, Miao, Liyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10496502/
https://www.ncbi.nlm.nih.gov/pubmed/37705739
http://dx.doi.org/10.7150/ijbs.87763

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