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Staphylococcus aureus planktonic but not biofilm environment induces an IFN-β macrophage immune response via the STING/IRF3 pathway

Chronic implant-related bone infections are a severe complication in orthopaedic surgery. Biofilm formation on the implant impairs the immune response, leading to bacterial persistence. In a previous study, we found that Staphylococcus aureus (SA) induced interferon regulatory factor 3 (IRF3) activa...

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Detalles Bibliográficos
Autores principales: Seebach, Elisabeth, Sonnenmoser, Gabriele, Kubatzky, Katharina F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10496530/
https://www.ncbi.nlm.nih.gov/pubmed/37655977
http://dx.doi.org/10.1080/21505594.2023.2254599