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Malignant catatonia responsive to low doses of lorazepam: case report: Catatonia maligna responsiva a baixas doses de lorazepam: relato de caso

CONTEXT: Catatonia can be divided into non-malignant or malignant. The latter is characterized by autonomic instability, exhibiting high fever, tachycardia and hypertension, and is regarded as a fulminant and rapidly progressive subtype. CASE REPORT: This article reports a case of malignant catatoni...

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Autores principales: Matias, Diego Fernando Moreira, Ando, Sabrina de Mello, Riera, Rachel, de Góis, Aécio Flávio Teixeira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Paulista de Medicina - APM 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10496534/
https://www.ncbi.nlm.nih.gov/pubmed/26465814
http://dx.doi.org/10.1590/1516-3180.2014.00052608
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author Matias, Diego Fernando Moreira
Ando, Sabrina de Mello
Riera, Rachel
de Góis, Aécio Flávio Teixeira
author_facet Matias, Diego Fernando Moreira
Ando, Sabrina de Mello
Riera, Rachel
de Góis, Aécio Flávio Teixeira
author_sort Matias, Diego Fernando Moreira
collection PubMed
description CONTEXT: Catatonia can be divided into non-malignant or malignant. The latter is characterized by autonomic instability, exhibiting high fever, tachycardia and hypertension, and is regarded as a fulminant and rapidly progressive subtype. CASE REPORT: This article reports a case of malignant catatonia in a 43-year-old patient who had been presenting psychiatric disorders for the last three years. The patient was stable, maintaining mutism, immobility and autonomic abnormalities. Oral lorazepam (1 mg every eight hours) was introduced and, in a few hours, the patient became afebrile. Two days later, the patient was already responding to verbal commands. CONCLUSIONS: Early intervention with lorazepam reduced the evolution of this patient to a fatal complication. Therefore, this case report sought to show that early diagnosis and intervention reduced the occurrence of serious and irreversible clinical outcomes.
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spelling pubmed-104965342023-09-13 Malignant catatonia responsive to low doses of lorazepam: case report: Catatonia maligna responsiva a baixas doses de lorazepam: relato de caso Matias, Diego Fernando Moreira Ando, Sabrina de Mello Riera, Rachel de Góis, Aécio Flávio Teixeira Sao Paulo Med J Case Report CONTEXT: Catatonia can be divided into non-malignant or malignant. The latter is characterized by autonomic instability, exhibiting high fever, tachycardia and hypertension, and is regarded as a fulminant and rapidly progressive subtype. CASE REPORT: This article reports a case of malignant catatonia in a 43-year-old patient who had been presenting psychiatric disorders for the last three years. The patient was stable, maintaining mutism, immobility and autonomic abnormalities. Oral lorazepam (1 mg every eight hours) was introduced and, in a few hours, the patient became afebrile. Two days later, the patient was already responding to verbal commands. CONCLUSIONS: Early intervention with lorazepam reduced the evolution of this patient to a fatal complication. Therefore, this case report sought to show that early diagnosis and intervention reduced the occurrence of serious and irreversible clinical outcomes. Associação Paulista de Medicina - APM 2015-10-09 /pmc/articles/PMC10496534/ /pubmed/26465814 http://dx.doi.org/10.1590/1516-3180.2014.00052608 Text en https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons license.
spellingShingle Case Report
Matias, Diego Fernando Moreira
Ando, Sabrina de Mello
Riera, Rachel
de Góis, Aécio Flávio Teixeira
Malignant catatonia responsive to low doses of lorazepam: case report: Catatonia maligna responsiva a baixas doses de lorazepam: relato de caso
title Malignant catatonia responsive to low doses of lorazepam: case report: Catatonia maligna responsiva a baixas doses de lorazepam: relato de caso
title_full Malignant catatonia responsive to low doses of lorazepam: case report: Catatonia maligna responsiva a baixas doses de lorazepam: relato de caso
title_fullStr Malignant catatonia responsive to low doses of lorazepam: case report: Catatonia maligna responsiva a baixas doses de lorazepam: relato de caso
title_full_unstemmed Malignant catatonia responsive to low doses of lorazepam: case report: Catatonia maligna responsiva a baixas doses de lorazepam: relato de caso
title_short Malignant catatonia responsive to low doses of lorazepam: case report: Catatonia maligna responsiva a baixas doses de lorazepam: relato de caso
title_sort malignant catatonia responsive to low doses of lorazepam: case report: catatonia maligna responsiva a baixas doses de lorazepam: relato de caso
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10496534/
https://www.ncbi.nlm.nih.gov/pubmed/26465814
http://dx.doi.org/10.1590/1516-3180.2014.00052608
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