Pleiotropic influence of DNA methylation QTLs on physiological and ageing traits

DNA methylation is influenced by genetic and non-genetic factors. Here, we chart quantitative trait loci (QTLs) that modulate levels of methylation at highly conserved CpGs using liver methylome data from mouse strains belonging to the BXD family. A regulatory hotspot on chromosome 5 had the highest...

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Detalles Bibliográficos
Autores principales: Mozhui, Khyobeni, Kim, Hyeonju, Villani, Flavia, Haghani, Amin, Sen, Saunak, Horvath, Steve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10496549/
https://www.ncbi.nlm.nih.gov/pubmed/37691384
http://dx.doi.org/10.1080/15592294.2023.2252631

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10496549/
https://www.ncbi.nlm.nih.gov/pubmed/37691384
http://dx.doi.org/10.1080/15592294.2023.2252631

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