Analysis of heparanase isoforms and cathepsin B in the plasma of patients with gastrointestinal carcinomas: analytical cross-sectional study: Análises das isoformas de heparanase e da catepsina B em plasma de pacientes com carcinomas gastrointestinais: estudo transversal analítico

CONTEXT AND OBJECTIVE: Heparanase-1 degrades heparan sulfate and has been correlated with tumor progression. Although the isoform heparanase-2 has no catalytic activity, it seems to be important for modulating heparanase-1 activity. Cathepsin B is a proteinase involved in tumor metastasis. The aim o...

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Detalles Bibliográficos
Autores principales: Melo, Carina Mucciolo, Origassa, Clarice Silvia Taemi, Theodoro, Thérèse Rachell, Matos, Leandro Luongo, Miranda, Thaís Aguilar, Accardo, Camila Melo, Bouças, Rodrigo Ippolito, Suarez, Eloah Rabello, Pares, Madalena Maria Nunes Silva, Waisberg, Daniel Reis, Toloi, Giovanna Canato, Nader, Helena Bonciani, Waisberg, Jaques, Pinhal, Maria Aparecida Silva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Paulista de Medicina - APM 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10496619/
https://www.ncbi.nlm.nih.gov/pubmed/25351637
http://dx.doi.org/10.1590/1516-3180.2013.7080003

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