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The prevalence of psychiatric disorders in patients with Multiple Sclerosis in Saudi Arabia: A cross-sectional multi-centered study

INTRODUCTION: Multiple sclerosis is considered one of the leading causes of neurological non-traumatic disability among young people. Given the chronic progressive nature of the disease, psychiatric disorders are more prevalent among those patients as reported in the literature; however, the data in...

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Autores principales: Alserihi, A., Alswat, A., Altirkistani, B., Baeshen, O., Alrushid, E., Alkhudair, J., Wadaan, O., Aldbas, A., Alsaleh, A., Al Malik, Y., Abulaban, A., Makkawi, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10496832/
http://dx.doi.org/10.1192/j.eurpsy.2023.1837
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author Alserihi, A.
Alswat, A.
Altirkistani, B.
Baeshen, O.
Alrushid, E.
Alkhudair, J.
Wadaan, O.
Aldbas, A.
Alsaleh, A.
Al Malik, Y.
Abulaban, A.
Makkawi, S.
author_facet Alserihi, A.
Alswat, A.
Altirkistani, B.
Baeshen, O.
Alrushid, E.
Alkhudair, J.
Wadaan, O.
Aldbas, A.
Alsaleh, A.
Al Malik, Y.
Abulaban, A.
Makkawi, S.
author_sort Alserihi, A.
collection PubMed
description INTRODUCTION: Multiple sclerosis is considered one of the leading causes of neurological non-traumatic disability among young people. Given the chronic progressive nature of the disease, psychiatric disorders are more prevalent among those patients as reported in the literature; however, the data in Saudi Arabia is lacking. OBJECTIVES: The study aimed to estimate the prevalence of psychiatric disorders among MS patient in Saudi Arabia. METHODS: This was a cross-sectional multi-centered study, including patients with multiple sclerosis. Participants were interviewed and asked to fill a validated survey that consisted of demographics, Patient Health Questionnaire-9 (PHQ-9), and Generalized Anxiety Disorder-7 (GAD-7) questionnaire. Descriptive statistics were performed, and the analysis were made using Chi-square, Fisher’s exact, and ANOVA tests as appropriate. RESULTS: A total of 192 participants were included in the study. Based on a cutoff score of > 10 in the GAD-7 and PHQ-9 scales, the prevalence of anxiety was 26.1% (n-50), with majority of the participants having minimal anxiety (40%); meanwhile, the prevalence of depression was 42.7% (n=82), and most of them had mild depression (30%). [table 1, image 1 and 2] Females participants significantly scored higher in GAD-7 and PHQ-9 compared to males (p-value= 0.0376 and 0.1134, respectively). [table 2 and 3] In addition, no significant association was detected between functional disability (EDSS score) and the prevalence of anxiety and depression. [Table: see text] [Table: see text] [Table: see text] Image: Image 2: CONCLUSIONS: This study reported high level of anxiety and depression among MS patients, with females being more affected. Since these co-morbid disorders could affect the disease course negatively, screening is of paramount significance. DISCLOSURE OF INTEREST: None Declared
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spelling pubmed-104968322023-09-13 The prevalence of psychiatric disorders in patients with Multiple Sclerosis in Saudi Arabia: A cross-sectional multi-centered study Alserihi, A. Alswat, A. Altirkistani, B. Baeshen, O. Alrushid, E. Alkhudair, J. Wadaan, O. Aldbas, A. Alsaleh, A. Al Malik, Y. Abulaban, A. Makkawi, S. Eur Psychiatry Abstract INTRODUCTION: Multiple sclerosis is considered one of the leading causes of neurological non-traumatic disability among young people. Given the chronic progressive nature of the disease, psychiatric disorders are more prevalent among those patients as reported in the literature; however, the data in Saudi Arabia is lacking. OBJECTIVES: The study aimed to estimate the prevalence of psychiatric disorders among MS patient in Saudi Arabia. METHODS: This was a cross-sectional multi-centered study, including patients with multiple sclerosis. Participants were interviewed and asked to fill a validated survey that consisted of demographics, Patient Health Questionnaire-9 (PHQ-9), and Generalized Anxiety Disorder-7 (GAD-7) questionnaire. Descriptive statistics were performed, and the analysis were made using Chi-square, Fisher’s exact, and ANOVA tests as appropriate. RESULTS: A total of 192 participants were included in the study. Based on a cutoff score of > 10 in the GAD-7 and PHQ-9 scales, the prevalence of anxiety was 26.1% (n-50), with majority of the participants having minimal anxiety (40%); meanwhile, the prevalence of depression was 42.7% (n=82), and most of them had mild depression (30%). [table 1, image 1 and 2] Females participants significantly scored higher in GAD-7 and PHQ-9 compared to males (p-value= 0.0376 and 0.1134, respectively). [table 2 and 3] In addition, no significant association was detected between functional disability (EDSS score) and the prevalence of anxiety and depression. [Table: see text] [Table: see text] [Table: see text] Image: Image 2: CONCLUSIONS: This study reported high level of anxiety and depression among MS patients, with females being more affected. Since these co-morbid disorders could affect the disease course negatively, screening is of paramount significance. DISCLOSURE OF INTEREST: None Declared Cambridge University Press 2023-07-19 /pmc/articles/PMC10496832/ http://dx.doi.org/10.1192/j.eurpsy.2023.1837 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Abstract
Alserihi, A.
Alswat, A.
Altirkistani, B.
Baeshen, O.
Alrushid, E.
Alkhudair, J.
Wadaan, O.
Aldbas, A.
Alsaleh, A.
Al Malik, Y.
Abulaban, A.
Makkawi, S.
The prevalence of psychiatric disorders in patients with Multiple Sclerosis in Saudi Arabia: A cross-sectional multi-centered study
title The prevalence of psychiatric disorders in patients with Multiple Sclerosis in Saudi Arabia: A cross-sectional multi-centered study
title_full The prevalence of psychiatric disorders in patients with Multiple Sclerosis in Saudi Arabia: A cross-sectional multi-centered study
title_fullStr The prevalence of psychiatric disorders in patients with Multiple Sclerosis in Saudi Arabia: A cross-sectional multi-centered study
title_full_unstemmed The prevalence of psychiatric disorders in patients with Multiple Sclerosis in Saudi Arabia: A cross-sectional multi-centered study
title_short The prevalence of psychiatric disorders in patients with Multiple Sclerosis in Saudi Arabia: A cross-sectional multi-centered study
title_sort prevalence of psychiatric disorders in patients with multiple sclerosis in saudi arabia: a cross-sectional multi-centered study
topic Abstract
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10496832/
http://dx.doi.org/10.1192/j.eurpsy.2023.1837
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