The Self-Assembly Soluplus Nanomicelles of Nobiletin in Aqueous Medium Based on Solid Dispersion and Their Increased Hepatoprotective Effect on APAP-Induced Acute Liver Injury

PURPOSE: APAP-induced liver injury (AILI) is a common cause of acute liver failure (ALF). Nobiletin (NOB) is a potential hepatoprotective agent for the treatment of APAP-induced liver injury. However, the poor solubility and low bioavailability of NOB hinders its application. In this study, a novel...

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Detalles Bibliográficos
Autores principales: Ning, Jinrong, Zheng, Guodong, Cai, Yi, Hu, Yunguang, Liu, Yiqi, Lai, Enping, Chen, Baizhong, Liu, Yujie, Liang, Ziqi, Fu, Jijun, Wei, Minyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10496926/
https://www.ncbi.nlm.nih.gov/pubmed/37705866
http://dx.doi.org/10.2147/IJN.S426703

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