Dectin-1 stimulation promotes a distinct inflammatory signature in the setting of HIV-infection and aging

Dectin-1 is an innate immune receptor that recognizes and binds β-1, 3/1, 6 glucans on fungi. We evaluated Dectin-1 function in myeloid cells in a cohort of HIV-positive and HIV-negative young and older adults. Stimulation of monocytes with β-D-glucans induced a pro-inflammatory phenotype in monocyt...

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Detalles Bibliográficos
Autores principales: Kumar, Archit, Wang, Jiawei, Esterly, Allen, Radcliffe, Chris, Zhou, Haowen, Wyk, Brent Vander, Allore, Heather G., Tsang, Sui, Barakat, Lydia, Mohanty, Subhasis, Zhao, Hongyu, Shaw, Albert C., Zapata, Heidi J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497004/
https://www.ncbi.nlm.nih.gov/pubmed/37606991
http://dx.doi.org/10.18632/aging.204927

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