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Inhibition of VCP modulates NF-κB signaling pathway to suppress multiple myeloma cell proliferation and osteoclast differentiation

Multiple myeloma (MM) is the second most common hematological malignancy, in which the dysfunction of the ubiquitin-proteasome pathway is associated with the pathogenesis. The valosin containing protein (VCP)/p97, a member of the AAA+ ATPase family, possesses multiple functions to regulate the prote...

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Detalles Bibliográficos
Autores principales: Wei, Rongfang, Cao, Yuhao, Wu, Hongjie, Liu, Xin, Jiang, Mingmei, Luo, Xian, Deng, Zhendong, Wang, Ze, Ke, Mengying, Zhu, Yongqiang, Chen, Siqing, Gu, Chunyan, Yang, Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497005/
https://www.ncbi.nlm.nih.gov/pubmed/37606987
http://dx.doi.org/10.18632/aging.204965