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The combination of RPA-CRISPR/Cas12a and Leptospira IgM RDT enhances the early detection of leptospirosis

BACKGROUND: Lack of available sensitive point-of-care testing is one of the primary obstacles to the rapid diagnosis of leptospirosis. The purpose of this study was to test the performance of two point-of-care tests, a clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associat...

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Detalles Bibliográficos
Autores principales: Jirawannaporn, Sirawit, Limothai, Umaporn, Tachaboon, Sasipha, Dinhuzen, Janejira, Kiatamornrak, Patcharakorn, Chaisuriyong, Watchadaporn, Srisawat, Nattachai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497128/
https://www.ncbi.nlm.nih.gov/pubmed/37624847
http://dx.doi.org/10.1371/journal.pntd.0011596