Clinical Outcomes and Prognostic Factors of Patients With Early Malignant Melanoma in One Latin American Country: Results of the Epidemiological Registry of Malignant Melanoma in Colombia Study

To describe the population with early malignant melanoma, we performed a cohort study on the basis of the Epidemiological Registry of Malignant Melanoma in Colombia-Asociacion Colombiana de Hematologia y Oncologia. From January 2011 until December 2021, 759 patients were included; the average age wa...

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Detalles Bibliográficos
Autores principales: Ospina Serrano, Aylen Vanessa, Contreras, Fernando, Triana, Iván, Sánchez-Vanegas, Guillermo, Ortíz, Juan David, Ramos, Pedro, Vargas, Claudia, Arango, Natalia, Idrobo, Henry, Munévar, Isabel, Yepes, Andrés, Mantilla, William, Jiménez, Paola, Rivas, Giovanna, Lema, Mauricio, Alcalá, Carmen, Gómez, Diego, Chinchia, Matilde, Barrero, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2023
Materias:
Original Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497268/
https://www.ncbi.nlm.nih.gov/pubmed/37216624
http://dx.doi.org/10.1200/GO.22.00377
Descripción
Sumario:To describe the population with early malignant melanoma, we performed a cohort study on the basis of the Epidemiological Registry of Malignant Melanoma in Colombia-Asociacion Colombiana de Hematologia y Oncologia. From January 2011 until December 2021, 759 patients were included; the average age was 66 years, 57% were women, acral lentiginous histology was found in 27.8% of patients, and the median follow-up was 36.5 months. The prognostic factors for overall survival in our population are Eastern Cooperative Oncology Group 3-4 (hazard ratio [HR], 13.8), stage III (HR, 5.07), received radiotherapy (HR, 3.38), ulceration on histology (HR, 2.68), chronic sun exposure (HR, 2.3), low income (HR, 2.04), previous local surgery (HR, 0.27), and have received adjuvant treatment (HR, 0.41).

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