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Clinical Outcomes and Prognostic Factors of Patients With Early Malignant Melanoma in One Latin American Country: Results of the Epidemiological Registry of Malignant Melanoma in Colombia Study
To describe the population with early malignant melanoma, we performed a cohort study on the basis of the Epidemiological Registry of Malignant Melanoma in Colombia-Asociacion Colombiana de Hematologia y Oncologia. From January 2011 until December 2021, 759 patients were included; the average age wa...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497268/ https://www.ncbi.nlm.nih.gov/pubmed/37216624 http://dx.doi.org/10.1200/GO.22.00377 |
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author | Ospina Serrano, Aylen Vanessa Contreras, Fernando Triana, Iván Sánchez-Vanegas, Guillermo Ortíz, Juan David Ramos, Pedro Vargas, Claudia Arango, Natalia Idrobo, Henry Munévar, Isabel Yepes, Andrés Mantilla, William Jiménez, Paola Rivas, Giovanna Lema, Mauricio Alcalá, Carmen Gómez, Diego Chinchia, Matilde Barrero, Angela |
author_facet | Ospina Serrano, Aylen Vanessa Contreras, Fernando Triana, Iván Sánchez-Vanegas, Guillermo Ortíz, Juan David Ramos, Pedro Vargas, Claudia Arango, Natalia Idrobo, Henry Munévar, Isabel Yepes, Andrés Mantilla, William Jiménez, Paola Rivas, Giovanna Lema, Mauricio Alcalá, Carmen Gómez, Diego Chinchia, Matilde Barrero, Angela |
author_sort | Ospina Serrano, Aylen Vanessa |
collection | PubMed |
description | To describe the population with early malignant melanoma, we performed a cohort study on the basis of the Epidemiological Registry of Malignant Melanoma in Colombia-Asociacion Colombiana de Hematologia y Oncologia. From January 2011 until December 2021, 759 patients were included; the average age was 66 years, 57% were women, acral lentiginous histology was found in 27.8% of patients, and the median follow-up was 36.5 months. The prognostic factors for overall survival in our population are Eastern Cooperative Oncology Group 3-4 (hazard ratio [HR], 13.8), stage III (HR, 5.07), received radiotherapy (HR, 3.38), ulceration on histology (HR, 2.68), chronic sun exposure (HR, 2.3), low income (HR, 2.04), previous local surgery (HR, 0.27), and have received adjuvant treatment (HR, 0.41). |
format | Online Article Text |
id | pubmed-10497268 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Wolters Kluwer Health |
record_format | MEDLINE/PubMed |
spelling | pubmed-104972682023-09-13 Clinical Outcomes and Prognostic Factors of Patients With Early Malignant Melanoma in One Latin American Country: Results of the Epidemiological Registry of Malignant Melanoma in Colombia Study Ospina Serrano, Aylen Vanessa Contreras, Fernando Triana, Iván Sánchez-Vanegas, Guillermo Ortíz, Juan David Ramos, Pedro Vargas, Claudia Arango, Natalia Idrobo, Henry Munévar, Isabel Yepes, Andrés Mantilla, William Jiménez, Paola Rivas, Giovanna Lema, Mauricio Alcalá, Carmen Gómez, Diego Chinchia, Matilde Barrero, Angela JCO Glob Oncol Original Reports To describe the population with early malignant melanoma, we performed a cohort study on the basis of the Epidemiological Registry of Malignant Melanoma in Colombia-Asociacion Colombiana de Hematologia y Oncologia. From January 2011 until December 2021, 759 patients were included; the average age was 66 years, 57% were women, acral lentiginous histology was found in 27.8% of patients, and the median follow-up was 36.5 months. The prognostic factors for overall survival in our population are Eastern Cooperative Oncology Group 3-4 (hazard ratio [HR], 13.8), stage III (HR, 5.07), received radiotherapy (HR, 3.38), ulceration on histology (HR, 2.68), chronic sun exposure (HR, 2.3), low income (HR, 2.04), previous local surgery (HR, 0.27), and have received adjuvant treatment (HR, 0.41). Wolters Kluwer Health 2023-05-22 /pmc/articles/PMC10497268/ /pubmed/37216624 http://dx.doi.org/10.1200/GO.22.00377 Text en © 2023 by American Society of Clinical Oncology https://creativecommons.org/licenses/by/4.0/Licensed under the Creative Commons Attribution 4.0 License: http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) |
spellingShingle | Original Reports Ospina Serrano, Aylen Vanessa Contreras, Fernando Triana, Iván Sánchez-Vanegas, Guillermo Ortíz, Juan David Ramos, Pedro Vargas, Claudia Arango, Natalia Idrobo, Henry Munévar, Isabel Yepes, Andrés Mantilla, William Jiménez, Paola Rivas, Giovanna Lema, Mauricio Alcalá, Carmen Gómez, Diego Chinchia, Matilde Barrero, Angela Clinical Outcomes and Prognostic Factors of Patients With Early Malignant Melanoma in One Latin American Country: Results of the Epidemiological Registry of Malignant Melanoma in Colombia Study |
title | Clinical Outcomes and Prognostic Factors of Patients With Early Malignant Melanoma in One Latin American Country: Results of the Epidemiological Registry of Malignant Melanoma in Colombia Study |
title_full | Clinical Outcomes and Prognostic Factors of Patients With Early Malignant Melanoma in One Latin American Country: Results of the Epidemiological Registry of Malignant Melanoma in Colombia Study |
title_fullStr | Clinical Outcomes and Prognostic Factors of Patients With Early Malignant Melanoma in One Latin American Country: Results of the Epidemiological Registry of Malignant Melanoma in Colombia Study |
title_full_unstemmed | Clinical Outcomes and Prognostic Factors of Patients With Early Malignant Melanoma in One Latin American Country: Results of the Epidemiological Registry of Malignant Melanoma in Colombia Study |
title_short | Clinical Outcomes and Prognostic Factors of Patients With Early Malignant Melanoma in One Latin American Country: Results of the Epidemiological Registry of Malignant Melanoma in Colombia Study |
title_sort | clinical outcomes and prognostic factors of patients with early malignant melanoma in one latin american country: results of the epidemiological registry of malignant melanoma in colombia study |
topic | Original Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497268/ https://www.ncbi.nlm.nih.gov/pubmed/37216624 http://dx.doi.org/10.1200/GO.22.00377 |
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