Cargando…

Non-COVID-19 Cutaneous Mucormycosis from a Plastic Surgical Perspective

Background  Cutaneous mucormycosis is a rare and fulminant infection associated with high mortality. Plastic surgeons come across this infection in the settings of road traffic accidents, surgical site infections, and as a secondary infection with underlying bacterial soft tissue infections. Due to...

Descripción completa

Detalles Bibliográficos
Autores principales: Brajesh, Vimalendu, Sharma, Sneha, Aggarwal, Aditya, Singh, Sukhdeep, Mahendru, Sanjay, Singh, Hardeep, Jain, Ankit, Jain, Rahul, Khazanchi, Rakesh Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Medical and Scientific Publishers Pvt. Ltd. 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497338/
https://www.ncbi.nlm.nih.gov/pubmed/37705818
http://dx.doi.org/10.1055/s-0043-1771294
_version_ 1785105284921819136
author Brajesh, Vimalendu
Sharma, Sneha
Aggarwal, Aditya
Singh, Sukhdeep
Mahendru, Sanjay
Singh, Hardeep
Jain, Ankit
Jain, Rahul
Khazanchi, Rakesh Kumar
author_facet Brajesh, Vimalendu
Sharma, Sneha
Aggarwal, Aditya
Singh, Sukhdeep
Mahendru, Sanjay
Singh, Hardeep
Jain, Ankit
Jain, Rahul
Khazanchi, Rakesh Kumar
author_sort Brajesh, Vimalendu
collection PubMed
description Background  Cutaneous mucormycosis is a rare and fulminant infection associated with high mortality. Plastic surgeons come across this infection in the settings of road traffic accidents, surgical site infections, and as a secondary infection with underlying bacterial soft tissue infections. Due to this infection's rarity and aggressive course, it is essential to initiate prompt multidisciplinary management at the first presentation. With this study, we aim to present a protocol for managing the condition. Methods  This is a retrospective observational study of patients with cutaneous mucormycosis managed at a tertiary care hospital from January 1, 2016 to November 30, 2022 excluding patients with mucormycosis who tested positive for coronavirus disease 2019. Results  Of 24 patients, 22 were males, and most were in the age group of 41 to 60 years. Sixteen patients survived and five out of eight deceased had comorbidities, six presented primarily without prior debridement, and six had trunk involvement. Conclusion  A high index of clinical suspicion is necessary for early diagnosis and management of patients with invasive cutaneous mucormycosis. A multidisciplinary approach with appropriate medical and surgical management can improve outcomes in cases that otherwise carry a high mortality rate.
format Online
Article
Text
id pubmed-10497338
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
record_format MEDLINE/PubMed
spelling pubmed-104973382023-09-13 Non-COVID-19 Cutaneous Mucormycosis from a Plastic Surgical Perspective Brajesh, Vimalendu Sharma, Sneha Aggarwal, Aditya Singh, Sukhdeep Mahendru, Sanjay Singh, Hardeep Jain, Ankit Jain, Rahul Khazanchi, Rakesh Kumar Indian J Plast Surg Background  Cutaneous mucormycosis is a rare and fulminant infection associated with high mortality. Plastic surgeons come across this infection in the settings of road traffic accidents, surgical site infections, and as a secondary infection with underlying bacterial soft tissue infections. Due to this infection's rarity and aggressive course, it is essential to initiate prompt multidisciplinary management at the first presentation. With this study, we aim to present a protocol for managing the condition. Methods  This is a retrospective observational study of patients with cutaneous mucormycosis managed at a tertiary care hospital from January 1, 2016 to November 30, 2022 excluding patients with mucormycosis who tested positive for coronavirus disease 2019. Results  Of 24 patients, 22 were males, and most were in the age group of 41 to 60 years. Sixteen patients survived and five out of eight deceased had comorbidities, six presented primarily without prior debridement, and six had trunk involvement. Conclusion  A high index of clinical suspicion is necessary for early diagnosis and management of patients with invasive cutaneous mucormycosis. A multidisciplinary approach with appropriate medical and surgical management can improve outcomes in cases that otherwise carry a high mortality rate. Thieme Medical and Scientific Publishers Pvt. Ltd. 2023-07-28 /pmc/articles/PMC10497338/ /pubmed/37705818 http://dx.doi.org/10.1055/s-0043-1771294 Text en Association of Plastic Surgeons of India. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. ( https://creativecommons.org/licenses/by-nc-nd/4.0/ ) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.
spellingShingle Brajesh, Vimalendu
Sharma, Sneha
Aggarwal, Aditya
Singh, Sukhdeep
Mahendru, Sanjay
Singh, Hardeep
Jain, Ankit
Jain, Rahul
Khazanchi, Rakesh Kumar
Non-COVID-19 Cutaneous Mucormycosis from a Plastic Surgical Perspective
title Non-COVID-19 Cutaneous Mucormycosis from a Plastic Surgical Perspective
title_full Non-COVID-19 Cutaneous Mucormycosis from a Plastic Surgical Perspective
title_fullStr Non-COVID-19 Cutaneous Mucormycosis from a Plastic Surgical Perspective
title_full_unstemmed Non-COVID-19 Cutaneous Mucormycosis from a Plastic Surgical Perspective
title_short Non-COVID-19 Cutaneous Mucormycosis from a Plastic Surgical Perspective
title_sort non-covid-19 cutaneous mucormycosis from a plastic surgical perspective
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497338/
https://www.ncbi.nlm.nih.gov/pubmed/37705818
http://dx.doi.org/10.1055/s-0043-1771294
work_keys_str_mv AT brajeshvimalendu noncovid19cutaneousmucormycosisfromaplasticsurgicalperspective
AT sharmasneha noncovid19cutaneousmucormycosisfromaplasticsurgicalperspective
AT aggarwaladitya noncovid19cutaneousmucormycosisfromaplasticsurgicalperspective
AT singhsukhdeep noncovid19cutaneousmucormycosisfromaplasticsurgicalperspective
AT mahendrusanjay noncovid19cutaneousmucormycosisfromaplasticsurgicalperspective
AT singhhardeep noncovid19cutaneousmucormycosisfromaplasticsurgicalperspective
AT jainankit noncovid19cutaneousmucormycosisfromaplasticsurgicalperspective
AT jainrahul noncovid19cutaneousmucormycosisfromaplasticsurgicalperspective
AT khazanchirakeshkumar noncovid19cutaneousmucormycosisfromaplasticsurgicalperspective