Cargando…

Whole Exome Analysis to Select Targeted Therapies for Patients with Metastatic Breast Cancer – A Feasibility Study

INTRODUCTION: The purpose of this feasibility study was to select targeted therapies according to “ESMO Scale for Clinical Actionability of molecular Targets (ESCAT)”. Data interpretation was further supported by a browser-based Treatment Decision Support platform (MH Guide, Molecular Health, Heidel...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jaeger, Bernadette Anna Sophia, Krawczyk, Natalia, Japp, Anna Sophia, Honisch, Ellen, Köhrer, Karl, Scheuring, Sibylle, Petzsch, Patrick, Neubauer, Hans, Volkmer, Anne Kathrin, Esposito, Irene, Ruckhäberle, Eugen, Niederacher, Dieter, Fehm, Tanja
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Georg Thieme Verlag KG 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497348/ https://www.ncbi.nlm.nih.gov/pubmed/37706056 http://dx.doi.org/10.1055/a-2150-9440

Ejemplares similares

Determination of the androgen receptor status of circulating tumour cells in metastatic breast cancer patients
por: Krawczyk, Natalia, et al.
Publicado: (2019)

Multiparametric Circulating Tumor Cell Analysis to Select Targeted Therapies for Breast Cancer Patients
por: Franken, André, et al.
Publicado: (2021)

Is the (Neo)adjuvant Therapy of Patients with Primary HER2-positive Breast Cancer Cost-Covering?: Process Cost Analysis of Neoadjuvant and Post-Neoadjuvant Systemic Therapy of Patients with Primary HER2-positive Breast Cancer
por: Krawczyk, Natalia, et al.
Publicado: (2022)

PGRMC1 Promotes Progestin-Dependent Proliferation of Breast Cancer Cells by Binding Prohibitins Resulting in Activation of ERα Signaling
por: Bai, Yingxue, et al.
Publicado: (2021)

Detection of circulating tumor cells in colorectal cancer patients using the GILUPI CellCollector: results from a prospective, single‐center study
por: Dizdar, Levent, et al.
Publicado: (2019)

Invasive Breast Carcinoma with Neuroendocrine Differentiation: A Single-Center Analysis of Clinical Features and Prognosis
por: Krawczyk, Natalia, et al.
Publicado: (2021)

Progesterone receptor membrane component 1 regulates lipid homeostasis and drives oncogenic signaling resulting in breast cancer progression
por: Asperger, Hannah, et al.
Publicado: (2020)

The effects of a music intervention during port catheter placement on anxiety and stress
por: Schaal, Nora K., et al.
Publicado: (2021)

Evaluation of Intraoperative Frozen Section Analysis with Final Histopathology Results for Sentinel Lymph Node Biopsy: Z0011 Criteria Eligible Versus Ineligible Breast Cancer Patients
por: Reinhardt, Florian, et al.
Publicado: (2022)

A Novel Workflow to Enrich and Isolate Patient-Matched EpCAM(high) and EpCAM(low/negative) CTCs Enables the Comparative Characterization of the PIK3CA Status in Metastatic Breast Cancer
por: Lampignano, Rita, et al.
Publicado: (2017)

Diagnostic Leukapheresis Enables Reliable Transcriptomic Profiling of Single Circulating Tumor Cells to Characterize Inter-Cellular Heterogeneity in Terms of Endocrine Resistance
por: Reinhardt, Florian, et al.
Publicado: (2019)

Correction to: Progesterone receptor membrane component 1 regulates lipid homeostasis and drives oncogenic signaling resulting in breast cancer progression
por: Asperger, Hannah, et al.
Publicado: (2021)

Expression of Stem Cell and Epithelial-Mesenchymal Transition Markers in Circulating Tumor Cells of Breast Cancer Patients
por: Krawczyk, Natalia, et al.
Publicado: (2014)

Insulin-Like Growth Factor 1 Attenuates the Pro-Inflammatory Phenotype of Neutrophils in Myocardial Infarction
por: Nederlof, Rianne, et al.
Publicado: (2022)

EpCAM-Independent Enrichment of Circulating Tumor Cells in Metastatic Breast Cancer
por: Schneck, Helen, et al.
Publicado: (2015)

Correction: EpCAM-Independent Enrichment of Circulating Tumor Cells in Metastatic Breast Cancer
por: Schneck, Helen, et al.
Publicado: (2016)

DanioCTC: Analysis of Circulating Tumor Cells from Metastatic Breast Cancer Patients in Zebrafish Xenografts
por: Reinhardt, Florian, et al.
Publicado: (2023)

Progesterone receptor membrane component 1 is phosphorylated upon progestin treatment in breast cancer cells
por: Willibald, Marina, et al.
Publicado: (2017)

Genomic characterization of mutant laboratory mouse strains by exome sequencing and annotation lift-over
por: Derdak, Sophia, et al.
Publicado: (2015)

Role of DNA methylation in miR-200c/141 cluster silencing in invasive breast cancer cells
por: Neves, Rui, et al.
Publicado: (2010)

The Role and Clinical Relevance of Disseminated Tumor Cells in Breast Cancer
por: Banys, Malgorzata, et al.
Publicado: (2014)

Clinical relevance of circulating tumor cells in ovarian, fallopian tube and peritoneal cancer
por: Banys-Paluchowski, Malgorzata, et al.
Publicado: (2020)

Post-Neoadjuvant Treatment Strategies in Breast Cancer
por: Matuschek, Christiane, et al.
Publicado: (2022)

Predictive Factors of Long-Term Survival after Neoadjuvant Radiotherapy and Chemotherapy in High-Risk Breast Cancer
por: Haussmann, Jan, et al.
Publicado: (2022)

The transcription factor reservoir and chromatin landscape in activated plasmacytoid dendritic cells
por: Mann-Nüttel, Ritu, et al.
Publicado: (2021)

Potential Role of Circulating Tumor Cell Detection and Monitoring in Breast Cancer: A Review of Current Evidence
por: Banys-Paluchowski, Malgorzata, et al.
Publicado: (2016)

Liquid Biopsy in Breast Cancer
por: Banys-Paluchowski, Maggie, et al.
Publicado: (2020)

Comparative analysis of EpCAM high-expressing and low-expressing circulating tumour cells with regard to their clonal relationship and clinical value
por: Franken, André, et al.
Publicado: (2023)

Measuring the course of anxiety in women giving birth by caesarean section: a prospective study
por: Hepp, Philip, et al.
Publicado: (2016)

Early Outcome, Cosmetic Result and Tolerability of an IOERT-Boost Prior to Adjuvant Whole-Breast Irradiation
por: Jazmati, Danny, et al.
Publicado: (2022)

Post-Neoadjuvant Treatment in HER2-Positive Breast Cancer: Escalation and De-Escalation Strategies
por: Krawczyk, Natalia, et al.
Publicado: (2022)

Changes in bone metabolic parameters in children with chronic myeloid leukemia on imatinib treatment
por: Jaeger, Bernadette Anna Sophia, et al.
Publicado: (2012)

Identification and characterization of OSTL (RNF217) encoding a RING-IBR-RING protein adjacent to a translocation breakpoint involving ETV6 in childhood ALL
por: Fontanari Krause, Luciana M., et al.
Publicado: (2014)

Macrophage Capping Protein CapG Is a Putative Oncogene Involved in Migration and Invasiveness in Ovarian Carcinoma
por: Glaser, J., et al.
Publicado: (2014)

Tumorigenic effects of human mesenchymal stromal cells and fibroblasts on bladder cancer cells
por: Frerichs, Lucie M., et al.
Publicado: (2023)

CDK4/6 inhibition presents as a therapeutic option for paediatric and adult germ cell tumours and induces cell cycle arrest and apoptosis via canonical and non-canonical mechanisms
por: Skowron, Margaretha A., et al.
Publicado: (2020)

Epigenetic Priming of Bladder Cancer Cells With Decitabine Increases Cytotoxicity of Human EGFR and CD44v6 CAR Engineered T-Cells
por: Grunewald, Camilla M., et al.
Publicado: (2021)

Combination of Decitabine and Entinostat Synergistically Inhibits Urothelial Bladder Cancer Cells via Activation of FoxO1
por: Wang, Chenyin, et al.
Publicado: (2020)

Antitumor activity of zoledronic acid in primary breast cancer cells determined by the ATP tumor chemosensitivity assay
por: Fehm, Tanja, et al.
Publicado: (2012)

Identifying Mitotic Kinesins as Potential Prognostic Biomarkers in Ovarian Cancer Using Bioinformatic Analyses
por: Liu, Hailun, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_m6jg3c5jkof9e60fq5q1bsmiht