Neurofilament light chain as a mediator between LRRK2 mutation and dementia in Parkinson’s disease

Elevated neurofilament light chain (NfL) levels have been associated with dementia in idiopathic Parkinson’s disease (iPD). To examine the baseline and longitudinal changes in NfL levels in GBA-PD, SNCA-PD, and LRRK2-PD and further investigate the association between these genetic mutations, NfL, an...

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Detalles Bibliográficos
Autores principales: Yang, Dehao, Xie, Haobo, Wu, Sheng, Ying, Chenxin, Chen, Yiqun, Ge, Yaoying, Yao, Ruotong, Li, Kun, Jiang, Zihan, Chen, Guangyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497522/
https://www.ncbi.nlm.nih.gov/pubmed/37699957
http://dx.doi.org/10.1038/s41531-023-00572-3

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