Cargando…

Real-world performance analysis of a novel computational method in the precision oncology of pediatric tumors

BACKGROUND: The utility of routine extensive molecular profiling of pediatric tumors is a matter of debate due to the high number of genetic alterations of unknown significance or low evidence and the lack of standardized and personalized decision support methods. Digital drug assignment (DDA) is a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vodicska, Barbara, Déri, Júlia, Tihanyi, Dóra, Várkondi, Edit, Kispéter, Enikő, Dóczi, Róbert, Lakatos, Dóra, Dirner, Anna, Vidermann, Mátyás, Filotás, Péter, Szalkai-Dénes, Réka, Szegedi, István, Bartyik, Katalin, Gábor, Krisztina Míta, Simon, Réka, Hauser, Péter, Péter, György, Kiss, Csongor, Garami, Miklós, Peták, István
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Nature Singapore 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497647/ https://www.ncbi.nlm.nih.gov/pubmed/36914906 http://dx.doi.org/10.1007/s12519-023-00700-2

Ejemplares similares

Efficacy of Incremental Next-Generation ALK Inhibitor Treatment in Oncogene-Addicted, ALK-Positive, TP53-Mutant NSCLC
por: Urbán, László, et al.
Publicado: (2020)

Personalized First-Line Treatment of Metastatic Pancreatic Neuroendocrine Carcinoma Facilitated by Liquid Biopsy and Computational Decision Support
por: Szkukalek, Judita, et al.
Publicado: (2021)

A computational method for prioritizing targeted therapies in precision oncology: performance analysis in the SHIVA01 trial
por: Petak, Istvan, et al.
Publicado: (2021)

Clinical Course of COVID-19 Disease in Children Treated With Neoplastic Diseases in Hungary
por: Müller, Judit, et al.
Publicado: (2022)

Molecular subtype specific efficacy of MEK inhibitors in pancreatic cancers
por: Brauswetter, Diána, et al.
Publicado: (2017)

Optimization and Development of Albumin–Biopolymer Bioconjugates with Solubility-Improving Properties
por: Pápay, Zsófia Edit, et al.
Publicado: (2021)

Clinical and health policy experiences with HPV prevalence within the Hungarian organized cervical cancer screening program
por: Vajda, Réka, et al.
Publicado: (2018)

Daily serum phosphate increase as early and reliable indicator of kidney injury in children with leukemia and lymphoma developing tumor lysis syndrome
por: Biró, Erika, et al.
Publicado: (2023)

Late mortality in survivors of childhood cancer in Hungary
por: Jakab, Zsuzsanna, et al.
Publicado: (2020)

Anxiety and depression among infertile women: a cross-sectional survey from Hungary
por: Lakatos, Enikő, et al.
Publicado: (2017)

Resolving Differential Diagnostic Problems in von Willebrand Disease, in Fibrinogen Disorders, in Prekallikrein Deficiency and in Hereditary Hemorrhagic Telangiectasia by Next-Generation Sequencing
por: Gindele, Réka, et al.
Publicado: (2021)

Recent Advances in the Management of Pediatric Acute Myeloid Leukemia—Report of the Hungarian Pediatric Oncology-Hematology Group
por: Gaál, Zsuzsanna, et al.
Publicado: (2021)

A unified data representation theory for network visualization, ordering and coarse-graining
por: Kovács, István A., et al.
Publicado: (2015)

Role of carotid duplex in the assessment of carotid artery restenosis after endarterectomy or stenting
por: Szegedi, István, et al.
Publicado: (2023)

Restriction Enzyme Body Doubles and PCR Cloning: On the General Use of Type IIS Restriction Enzymes for Cloning
por: Tóth, Eszter, et al.
Publicado: (2014)

Therapeutic strategies in the early stages of Parkinson’s disease: a cross-sectional evaluation of 15 years’ experience with a large cohort of Romanian patients
por: Szász, József Attila, et al.
Publicado: (2019)

Towards a Better Understanding of the Post-Gastric Behavior of Enteric-Coated Formulations
por: Katona, Miklós Tamás, et al.
Publicado: (2022)

Multi-Compartmental Dissolution Method, an Efficient Tool for the Development of Enhanced Bioavailability Formulations Containing Poorly Soluble Acidic Drugs
por: Katona, Miklós Tamás, et al.
Publicado: (2023)

Incorporation of α2-Plasmin Inhibitor into Fibrin Clots and Its Association with the Clinical Outcome of Acute Ischemic Stroke Patients
por: Bagoly, Zsuzsa, et al.
Publicado: (2021)

Deep Sequencing of Porcine Reproductive and Respiratory Syndrome Virus ORF7: A Promising Tool for Diagnostics and Epidemiologic Surveillance
por: Jakab, Szilvia, et al.
Publicado: (2023)

Serine protease inhibitors of the whirling disease parasite Myxobolus cerebralis (Cnidaria, Myxozoa): Expression profiling and functional predictions
por: Eszterbauer, Edit, et al.
Publicado: (2021)

PersonALL: a genetic scoring guide for personalized risk assessment in pediatric B-cell precursor acute lymphoblastic leukemia
por: Bedics, Gábor, et al.
Publicado: (2023)

Comparison of accuracy between FSL’s FIRST and Freesurfer for caudate nucleus and putamen segmentation
por: Perlaki, Gabor, et al.
Publicado: (2017)

The Effect of the Particle Size Reduction on the Biorelevant Solubility and Dissolution of Poorly Soluble Drugs with Different Acid-Base Character
por: Csicsák, Dóra, et al.
Publicado: (2023)

Preparation of 2-phospholene oxides by the isomerization of 3-phospholene oxides
por: Bagi, Péter, et al.
Publicado: (2020)

Anticonvulsant Action and Long-Term Effects of Chronic Cannabidiol Treatment in the Rat Pentylenetetrazole-Kindling Model of Epilepsy
por: Gáll, Zsolt, et al.
Publicado: (2022)

Maternal Smoking Highly Affects the Function, Membrane Integrity, and Rheological Properties in Fetal Red Blood Cells
por: Dugmonits, Krisztina N., et al.
Publicado: (2019)

Erratum to “Maternal Smoking Highly Affects the Function, Membrane Integrity, and Rheological Properties in Fetal Red Blood Cells”
por: Dugmonits, Krisztina N., et al.
Publicado: (2021)

A Foldamer-Dendrimer Conjugate Neutralizes Synaptotoxic β-Amyloid Oligomers
por: Fülöp, Lívia, et al.
Publicado: (2012)

Ion Specific Effects on the Stability of Halloysite Nanotube Colloids—Inorganic Salts versus Ionic Liquids
por: Katana, Bojana, et al.
Publicado: (2020)

Delamination of Layered Double Hydroxide in Ionic Liquids under Ambient Conditions
por: Takács, Dóra, et al.
Publicado: (2022)

Case Report: A Child With Hemophilia A Serves as Donor for Hematopoietic Stem Cell Transplantation to Cure His Brother’s Severe Aplastic Anemia
por: Kertész, Gabriella, et al.
Publicado: (2022)

The role of urinary N-acetyl-β-D-glucosaminidase in early detection of acute kidney injury among pediatric patients with neoplastic disorders in a retrospective study
por: Bíró, Erika, et al.
Publicado: (2022)

Novel RB1 and MET Gene Mutations in a Case with Bilateral Retinoblastoma Followed by Multiple Metastatic Osteosarcoma
por: Mokánszki, Attila, et al.
Publicado: (2020)

Variation in Nectar Volume and Sugar Concentration of Allium ursinum L. ssp. ucrainicum in Three Habitats
por: Farkas, Ágnes, et al.
Publicado: (2012)

Progestogen-induced alterations and their ecological relevance in different embryonic and adult behaviours of an invertebrate model species, the great pond snail (Lymnaea stagnalis)
por: Svigruha, Reka, et al.
Publicado: (2020)

Efficacy of Treatments in Nonarteritic Ischemic Optic Neuropathy: A Systematic Review and Meta-Analysis
por: Lantos, Krisztina, et al.
Publicado: (2022)

P06-05 Physical activity patterns of Hungarian women of reproductive age, preliminary study of the EUPASMOS project
por: Premusz, Viktoria, et al.
Publicado: (2022)

P06-03 Associations between walkability and physical activity of Hungarian adults, preliminary study of the EUPASMOS project
por: Makai, Alexandra, et al.
Publicado: (2022)

Electrospray ionization–tandem mass spectrometric study of fused nitrogen‐containing ring systems
por: Krajsovszky, Gábor, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_3j9vedgq78mhdu0q8db96pof5d