Synthesis and cytotoxicity evaluation of novel 1,8-acridinedione derivatives bearing phthalimide moiety as potential antitumor agents

In this study, we aimed to develop hybrid antitumor compounds by synthesizing and characterizing novel N-substituted acrididine-1,8-dione derivatives, designed as hybrids of phthalimide and acridine-1,8-diones. We employed a three-step synthetic strategy and characterized all compounds using IR, (1)...

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Detalles Bibliográficos
Autores principales: Khatab, Hassan A., Hammad, Sherif F., El‐Fakharany, Esmail M., Hashem, Ahmed I., El-Helw, Eman A. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497682/
https://www.ncbi.nlm.nih.gov/pubmed/37699954
http://dx.doi.org/10.1038/s41598-023-41970-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497682/
https://www.ncbi.nlm.nih.gov/pubmed/37699954
http://dx.doi.org/10.1038/s41598-023-41970-0

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